University Of Edinburgh

This study is testing whether a daily capsule called MitoQ can help people with moderate ulcerative colitis (UC) during a flare-up. UC causes painful inflammation and ulcers in the large bowel. Researchers think MitoQ works by protecting the tiny 'batteries' inside gut cells, whi…

This study aimed to see if adding a daily MitoQ antioxidant capsule to standard treatment could better control ulcerative colitis in children and teens. It planned to test if MitoQ improved symptoms, reduced gut inflammation, and helped patients avoid stronger medications like st…

This study is testing if performing heart valve replacement surgery earlier than current guidelines recommend can improve outcomes for patients with severe aortic stenosis. It focuses on patients who have no symptoms but show early signs of heart muscle scarring on an MRI scan. T…

This study aims to see if a special heart scan can find hidden heart disease in people who went to the hospital with chest pain but were sent home after tests ruled out a heart attack. Researchers will use a CT scan to look for problems in patients who have low levels of a heart …

This study aimed to compare a new, gentler diagnostic method called a corneal impression membrane (a soft swab) against the standard, more uncomfortable corneal scrape for identifying the germs causing serious eye infections (microbial keratitis). The goal was to see if the swab …

This study is testing a computer-based tool called CoDE-HF that helps emergency room doctors diagnose acute heart failure more quickly and accurately. It works by combining a standard blood test result with basic patient information to calculate the likelihood of heart failure. T…

This study is testing whether a new, faster process can assess a person's risk for serious heart problems after they report new chest pain. About 500 people referred by their doctor for possible angina will use digital questionnaires and simple home tests. The goal is to see if a…

This study is testing if using a detailed heart scan (CTCA) to guide treatment is better at preventing fatal heart attacks than the current standard method, which uses a general risk score. It involves over 6,000 middle-aged adults in Scotland who have risk factors for heart dise…

This study is a 5-year extension to monitor people with a high genetic risk for Paget's disease of the bone. It follows up on 287 participants from a previous trial that tested whether an early drug treatment could prevent bone damage. The main goal is to see if preventing early …

This UK trial is testing whether giving blood transfusions to intensive care unit (ICU) survivors with low red blood cell counts (anemia) helps them recover their strength and quality of life faster. It compares the current standard approach of giving fewer transfusions to a more…

This study is not testing a treatment. Its goal is to plan a better, larger future research project for strokes caused by bleeding in the brain (intracerebral haemorrhage). Researchers are asking stroke survivors, their carers, and doctors in Scotland what they think about a new …

This study is testing whether a new AI-powered video game simulator can train doctors in keyhole surgery skills better and faster than the standard training box. 157 medical students and junior doctors are randomly assigned to train with either the game or the box, then their ski…

This study is a survey asking dentists in two UK regions about their use of Silver Diamine Fluoride (SDF), a liquid that can stop tooth decay in children without drilling. The goal is to understand why this simple treatment isn't used more often by learning about dentists' knowle…

This study follows golfers who get hip, knee, or shoulder replacement surgery to see how many return to golf, how long it takes, and how their game changes. Researchers will track 124 patients for one year through questionnaires about their golf activity, mobility, and joint func…

This study aimed to understand why some people get a positive result on a common stool test for colon cancer, but then a follow-up colonoscopy finds nothing wrong. Researchers wanted to check if a person's genetic tendency to bleed a little more easily could cause these 'false po…

This study aims to develop a genetic test to predict a person's risk of developing Paget's disease of bone, a condition that can cause pain, deformity, and fractures. Researchers are enrolling 135 people over age 45 who have a parent or sibling with the disease. They will analyze…

This study aims to better understand brain oxygen levels in newborns at high risk of brain injury. Researchers will use a safe, non-invasive sensor to monitor oxygen in the brains of 99 babies: some born very early and others receiving cooling treatment for oxygen deprivation at …

This study aims to understand how receiving information about heart disease risk influences people's lifestyle habits. It follows 400 participants already enrolled in a larger heart attack prevention trial. Researchers will track changes in diet, smoking, and activity over 6 mont…

This study aims to understand why the standard treatment for atrial fibrillation (AFib) doesn't work for everyone. Researchers will create detailed computer models of patients' hearts to identify the unique electrical circuits causing their irregular heartbeat. The goal is to gat…

This study aims to understand how empathy changes over time in people with borderline personality disorder (BPD). Researchers will follow about 30 participants for two years, using computer tests and questionnaires to measure their ability to understand others' feelings. The goal…