New study aims to predict Paget's disease before it strikes

NCT ID NCT05309954

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study looks at whether a genetic test can predict who will develop Paget's disease of the bone, a condition that can cause pain, deformity, and hearing loss. Researchers are studying 135 people aged 45 and older who have a parent or sibling with Paget's but do not have the disease themselves. Participants get a bone scan at the start and again after five years, along with blood, saliva, and stool tests, to see how well genetic markers predict the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Osteitis Deformans Paget disease bone Paget disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NHS Lothian

    Edinburgh, EH4 2XU, United Kingdom