University Of Edinburgh
Clinical trials sponsored by University Of Edinburgh, explained in plain language.
-
Brittle bone breakthrough? new combo aims to cut fractures in OI
Disease control CompletedThis study tested whether a two-year course of teriparatide followed by a single infusion of zoledronic acid can reduce fractures in adults with osteogenesis imperfecta (brittle bone disease). 350 participants were randomly assigned to receive either the drug combo or standard ca…
Phase: PHASE4 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 17, 2026 02:18 UTC
-
Donor cells show promise against Post-Transplant cancer in landmark trial
Disease control CompletedThis study tested a treatment for a rare cancer called post-transplant lymphoproliferative disease (PTLD) that can occur after an organ transplant. The cancer is linked to the Epstein-Barr virus. Researchers gave patients donor white blood cells trained to kill virus-infected cel…
Phase: PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 17, 2026 02:03 UTC
-
PET scan finds hidden heart danger; drug may cut risk
Disease control CompletedThis study looked at whether a blood thinner called ticagrelor can reduce heart attack risk in people with high-risk fatty plaques in their heart arteries. Researchers used a special PET scan to find patients with recently ruptured plaques that hadn't caused symptoms. The goal wa…
Phase: PHASE2, PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 17, 2026 02:03 UTC
-
Can cheap heart drugs save lives from pesticide poisoning?
Disease control CompletedThis study tested whether adding magnesium or nimodipine (drugs normally used for heart conditions) to standard treatment could help people who intentionally poisoned themselves with certain insecticides. Over 1700 adults took part. The goal was to see if these extra drugs reduce…
Phase: PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
-
Water workouts vs land therapy: which eases back pain best?
Symptom relief CompletedThis study looked at how water-based and land-based exercises affect chronic low back pain in adults aged 18 to 65. Over 12 weeks, 32 participants did supervised exercises in a pool or on land. The goal was to see which type of exercise better reduces pain, improves daily functio…
Phase: NA • Sponsor: University of Edinburgh • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
-
Can a high-tech insulin system and low-carb diet fix a dangerous diabetes complication?
Knowledge-focused CompletedThis study looked at 24 people with long-standing type 1 diabetes who have lost their ability to produce glucagon, a hormone that raises blood sugar when it gets too low. Researchers wanted to see if using an automated insulin delivery system plus a low-carbohydrate diet for 8 mo…
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 17, 2026 02:18 UTC
-
Could a heart drug shield blood vessels from reperfusion damage?
Knowledge-focused CompletedThis study tested whether rotigaptide, a drug that improves cell communication, can protect blood vessel function after temporary blockage and restoration of blood flow. Twelve healthy men participated, and researchers measured changes in forearm blood flow. The goal was to under…
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
-
Heart attack drug duration debate: shorter may be safer
Knowledge-focused CompletedThis study looked at how long people who had a heart attack should take two blood thinners (aspirin plus another drug) to prevent future heart problems. Taking them longer can lower the risk of clots but raises the chance of dangerous bleeding. The trial tracked over 5,000 patien…
Phase: PHASE4 • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
-
Probiotic study probes Gut-Brain link in Parkinson's
Knowledge-focused CompletedThis study looked at whether a probiotic called Bacillus subtilis can change certain markers in the gut and blood of people with Parkinson's disease. 26 participants took the probiotic or a placebo to see how it affected their gut bacteria, blood fats, inflammation, and other hea…
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 17, 2026 02:04 UTC
-
Borderline personality disorder empathy study reveals new insights
Knowledge-focused CompletedThis study looked at how empathy works in people with borderline personality disorder (BPD). Researchers used a computer test and questionnaires to measure two types of empathy: understanding others' thoughts and feeling others' emotions. About 30 participants were followed for 2…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 17, 2026 02:03 UTC
-
UK study maps rare nerve condition to improve care
Knowledge-focused CompletedThis study looked at 621 adults in the UK who had cauda equina syndrome, a rare condition where nerves at the bottom of the spine are squeezed. Researchers collected information on symptoms, treatments, and recovery to understand how the condition is managed and to help set bette…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
-
Scientists hunt for clues to stop cancer weight loss
Knowledge-focused CompletedThis study looked at why many cancer patients lose weight and muscle, a condition called cachexia. Researchers collected tissue and blood samples from 282 people during cancer surgery and compared them to samples from patients having surgery for non-cancer issues. They also measu…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
-
New imaging sheds light on hidden heart clots
Knowledge-focused CompletedThis study looked at 100 people who recently had a major heart attack to better understand blood clots that can form in the heart. Using a special PET/MR scan, researchers tracked clot activity in the heart and brain. The goal was to learn how these clots develop and resolve, whi…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 08, 2026 12:04 UTC