University Of Edinburgh

This study tested whether a two-year course of teriparatide (a bone-building drug) followed by a single infusion of zoledronic acid (a bone-strengthening drug) could reduce fractures in adults with osteogenesis imperfecta, also known as brittle bone disease. 350 participants were…

This study tested whether specially treated donor white blood cells could help treat a type of lymph cancer that sometimes occurs after an organ transplant. The cancer is linked to the Epstein-Barr virus. Fifty transplant recipients took part. The goal was to see if adding these …

This study looks at whether a blood thinner called ticagrelor can lower heart attack risk in people with high-risk fatty plaques in their heart arteries. Researchers used a special PET scan to find these plaques in 220 patients with coronary artery disease. Participants took eith…

This study tested whether adding magnesium sulfate or nimodipine (drugs usually used for heart conditions) to standard treatment could help people who poisoned themselves with pesticides. Over 1,700 adults in medical wards were enrolled. The main goal was to see if these drugs re…

This study looked at whether aquatic (water) exercises or land exercises work better for adults with chronic low back pain. Thirty-two people aged 18 to 65 took part in a 12-week supervised program. Researchers measured pain, daily function, sleep quality, and quality of life to …

This study looked at how children with cerebral palsy, their parents, and healthcare professionals experience sleep disordered breathing and its management. Researchers interviewed 24 participants to understand the challenges and what helps or hinders treatment. The goal was to g…

This study tracked 60 children aged 5 to 15 who survived a near fatal asthma attack in the UK and Ireland. Researchers collected data on risk factors, medical care, and social and environmental influences. The goal is to create better care guidelines and reduce future risks.

This study enrolled 91 people with atrial fibrillation to see if computer simulations can identify the main electrical problem causing their irregular heartbeat. Participants had heart imaging, mapping, and symptom tracking before and after a standard ablation procedure. The goal…

This study looked at how empathy works in people with borderline personality disorder (BPD). Researchers used a computer test and questionnaires to measure two types of empathy: understanding others' thoughts and feeling their emotions. About 30 participants were assessed four ti…

This study tested whether a daily probiotic supplement called Bacillus subtilis can change certain gut bacteria and blood markers in people with Parkinson's disease. Twenty-six participants took either the probiotic or a placebo for a period. The goal was to see if the supplement…

This study looked at 100 people who recently had a major heart attack to better understand blood clots that can form in the heart's main pumping chamber. Using special PET/MR scans, researchers tracked clot activity in the heart and brain over several months. The goal was to lear…

This study looked at how long people who had a heart attack should take two blood-thinning medicines (aspirin plus a second drug). About 5,000 patients were randomly assigned to shorter or longer treatment. The goal was to find the best balance between preventing another heart at…

This study looks at whether using an automated insulin delivery system (a smart insulin pump and continuous glucose monitor) along with a low-carbohydrate diet can help restore the body's natural glucagon response to low blood sugar in people with type 1 diabetes. The glucagon re…

This study looked at why many cancer patients lose muscle and weight, a condition called cachexia. Researchers collected samples of muscle, fat, blood, and urine from 282 people during cancer surgery and compared them with samples from non-cancer patients. They also measured phys…

This study looked at 621 adults in the UK who had cauda equina syndrome, a rare but serious condition where nerves at the bottom of the spine are compressed. Researchers tracked how patients were diagnosed, treated, and how they recovered. The goal was to gather accurate informat…

This study tested whether rotigaptide, a drug that improves cell communication, can protect blood vessel function after a temporary blockage of blood flow (ischemia-reperfusion injury). Twelve healthy men received the drug or a placebo while their forearm blood flow was measured.…