Immune cell therapy shows promise for Post-Transplant cancer

NCT ID NCT00033475

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether specially treated donor white blood cells could help treat a type of lymph cancer that sometimes occurs after an organ transplant. The cancer is linked to the Epstein-Barr virus. Fifty transplant recipients took part. The goal was to see if adding these donor cells to standard care (reducing immune-suppressing drugs) led to better tumor shrinkage and survival.

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Conditions

The condition(s) this trial relates to.

lymphoproliferative syndrome post-transplant lymphoproliferative disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Birmingham Children's Hospital

    Birmingham, England, B4 6NH, United Kingdom

  • Central Manchester and Manchester Children's University Hospitals NHS Trust

    Manchester, England, M27 4HA, United Kingdom

  • Institute of Cancer Research - UK

    Sutton, England, SM2 5NG, United Kingdom

  • King's College Hospital

    London, England, SE5 8RX, United Kingdom

  • Northern General Hospital

    Sheffield, England, S5 7AU, United Kingdom

  • Papworth Hospital

    Cambridge, England, CB3 8RE, United Kingdom

  • Royal Free and University College Medical School

    London, England, NW3 2PF, United Kingdom

  • Royal Infirmary - Castle

    Glasgow, Scotland, G4 0SF, United Kingdom

  • Royal Infirmary of Edinburgh at Little France

    Edinburgh, Scotland, EH16 4SA, United Kingdom

  • University of Edinburgh

    Edinburgh, Scotland, EH8 1QH, United Kingdom

  • University of Edinburgh Laboratory for Clinical and Molecular Virology

    Edinburgh, Scotland, EH9 1QH, United Kingdom

  • Wythenshawe Hospital

    Manchester, England, M23 9LJ, United Kingdom