Could cheap heart drugs save lives from pesticide poisoning?
NCT ID NCT03925025
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding magnesium sulfate or nimodipine (drugs usually used for heart conditions) to standard treatment could help people who poisoned themselves with pesticides. Over 1,700 adults in medical wards were enrolled. The main goal was to see if these drugs reduced deaths before leaving the hospital.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Magnesium sulfate and nimodipine
- What this could lead to
- If effective, these cheap, widely available drugs could become a standard addition to current treatment, potentially saving many lives from pesticide poisoning.
- What could go wrong
- This is a completed Phase 3 trial, but results are not yet reported. The drugs may not improve survival over standard care, and side effects like low blood pressure are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chattogram Medical College Hospital
Chittagong, 4203, Bangladesh
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Jashore Medical College Hospital
Jessore, Bangladesh
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Khulna Medical College Hospital
Khulna, Bangladesh
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Rajshahi Medical College Hospital
Rajshahi, Rajshahi Division, 6100, Bangladesh
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Rangpur Medical College Hospital
Rangpur City, Bangladesh
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Shaheed Ziaur Rahman Medical College
Bogra, Silimpur, 5800, Bangladesh
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Sylhet MAG Osmani Medical College Hospital
Sylhet, Bangladesh
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