University Hospital, Tours

This study tests whether a structured diet and exercise program can increase lean muscle mass in adults with cystic fibrosis who are already taking the medication Trikafta. About 100 participants will be followed for 12 months. The goal is to improve muscle strength and overall h…

This study tests whether using a diuretic (water pill) as the second blood pressure medication, after an ACE inhibitor or ARB, works better than usual care for people with moderate to severe chronic kidney disease and uncontrolled high blood pressure. About 720 adults will take p…

This study tests whether serving food in easy-to-grip, bite-sized pieces (finger food) helps elderly residents in care homes eat more, gain weight, and enjoy meals more. Researchers will track weight, food intake, and independence in 30 participants aged 75 and older who are unde…

This study looks at 100 adults with sickle cell disease who are in intensive care for severe pain crises. Researchers want to see if kidney function affects how the body clears morphine, which might explain why standard doses often don't relieve pain. By measuring morphine levels…