University Hospital, Clermont-ferrand

This study aims to determine whether putting stroke patients fully to sleep (general anesthesia) or keeping them lightly sedated (procedural sedation) during emergency clot removal surgery leads to better recovery. Researchers will compare these two common anesthesia approaches i…

This study aims to see if an MRI scan for Crohn's disease works just as well without requiring patients to drink a special liquid that distends their bowels, a process many find unpleasant. Researchers will compare two MRI scans—one with the standard drink and one without—in 60 a…

This study is testing whether a simple blood test can accurately detect brain bleeding in older adults hospitalized after repeated falls. Researchers will measure two specific proteins in the blood to see if this test can work as well as a brain CT scan, which is often difficult …

This study aims to see if a gentle, non-invasive brain stimulation technique, used early during standard rehabilitation, can prevent the development of chronic nerve pain after a stroke. It will involve 60 people who have recently had a stroke but do not yet have nerve pain. Part…

This study aims to check the real-world safety and effectiveness of two already-available throat sprays for easing coughs from common colds and similar viral infections. It will involve about 58 adults with a recent cough, who will use one of the sprays for a week and report thei…

This study follows head and neck cancer survivors who receive custom facial prostheses to restore their appearance and function. Researchers will measure how well patients can chew, swallow, and speak before and after getting their prosthesis, and track changes in their quality o…

This study aims to check how well four already-available nasal products work for easing symptoms of the common cold, sinus infections, and sore throats. Researchers will follow 150 adults in France who have recently caught a cold, tracking their symptoms and any side effects over…

This study aims to see if it's safe and practical for intensive care unit (ICU) patients to have visits from their own pet dogs. Researchers will carefully monitor 21 adult ICU patients and their dogs during short, supervised visits. The main goal is to check if these visits can …

This study aims to see if a machine that helps people cough is better than manual chest physiotherapy at clearing mucus from the lungs of hospitalized elderly patients. It will involve 120 participants aged 60 and over who have difficulty coughing effectively due to lung congesti…

This study aims to understand how a common gut bacteria, Enterococcus faecalis, escapes the intestines and causes serious heart valve infections. Researchers will examine 90 hospitalized patients with this bacteria in their blood to map where it comes from and how it travels. The…

This study aims to understand if regularly consuming artificial sweeteners changes how different parts of the brain communicate. Researchers will use MRI brain scans to compare healthy young adults who rarely use sweeteners with those who use them often. They will also scan some …

This study aims to understand if having less muscle mass increases the risk of serious bleeding in people aged 70 and older who take common blood-thinning pills. Researchers will compare the muscle mass of 110 participants who have had a bleeding event with those who have not. Th…

This study aims to understand why it's so difficult for families to change sugary eating habits after their young child has undergone major dental surgery for severe cavities. Researchers will interview about 30 parents in France whose children (under age 6) had this surgery to i…

This study aims to understand why people with Fibrous Dysplasia/McCune-Albright syndrome (FD/MAS) experience chronic bone pain. Researchers will compare pain sensitivity and processing in 40 adults with FD/MAS to healthy volunteers. The goal is to learn if the brain and nervous s…

This study aims to understand why some people with Parkinson's disease who also have a specific sleep disorder (REM sleep behavior disorder) might be at higher risk for developing impulse control problems. Researchers will use advanced brain scans (PET-MRI) to compare the brain's…

This study aims to understand if patients who need an emergency breathing tube are more likely to develop pneumonia compared to those who get one in a planned, non-emergency setting. Researchers will review the medical records of 600 adults who were intubated and stayed in intens…

This small study aims to understand how a single session of moderate cycling affects the levels of two specific proteins in the blood of people with liver cancer. Researchers will measure these proteins before and after the exercise in 12 participants. The goal is to gather infor…

This study looks back at patients who were in a remote heart failure monitoring program but were later taken off it because they no longer met the official criteria. Researchers want to see if these patients truly have a low risk of their heart condition getting worse after stopp…

This study aims to understand if a specific type of immune cell, called a regulatory T cell, works differently in people with chronic migraine. Researchers will compare blood samples from 24 female participants with chronic migraine to samples from healthy women. The goal is to l…