University Hospital, Clermont-ferrand

This study compares two treatments for Crohn's disease and ulcerative colitis: using the drug infliximab alone versus combining it with another immune-suppressing drug. The goal is to see if the single drug can keep patients in remission without steroids just as well as the combo…

This study tests a special 'smart duvet' that uses built-in sensors to track movement and estimate sleep. Researchers want to see if it works as well as the standard sleep lab test (video-polysomnography). The study includes 50 people with sleep disorders and healthy volunteers.

This study tests a nasal spray device called MIG-SPRAY in 45 adults with migraine to see how well it is tolerated. Participants are randomly assigned to use the device or not, and they report any side effects and migraine episodes daily. The goal is to compare side effects, migra…

This study looks at whether a new online tool helps healthcare teams choose and track their own quality goals. About 60 clinics in France will use the tool at different times, and researchers will compare their progress over several years. The goal is to see if having easy access…

This study looks at how breast cancer itself (before any treatment) might affect a woman's eggs and ability to preserve fertility. Researchers will compare egg quality and hormone responses between 100 women with breast cancer and healthy egg donors. The goal is to understand why…

This study looks at whether getting advice from an expert helps doctors better manage severe bleeding in patients taking blood thinners. About 1000 adults will take part, and their care will follow either standard practice or include expert guidance. Researchers will compare how …

This study looks at how fast risankizumab (Skyrizi) heals all layers of the gut in people with Crohn's disease. Instead of repeated colonoscopies, researchers use intestinal ultrasound to check healing at 4 and 12 weeks. About 109 adults starting risankizumab in routine care will…

This study looks at how much people trust institutions (like health organizations) when it comes to advice about physical activity. Researchers will ask 2000 volunteers questions about their trust levels and factors like age, lifestyle, and background. The goal is to understand w…