University Hospital, Clermont-ferrand

This study looks at whether using just one medication (infliximab) under the skin works as well as using it together with another immune-suppressing drug for people with Crohn's disease or ulcerative colitis. About 420 adults who have already started infliximab will be followed f…

This trial tests a nasal spray called MIG-SPRAY for preventing migraines in 45 adults aged 18-55. The spray forms a protective film inside the nose to possibly stop migraine triggers. Participants use it three times daily for three months, and researchers track side effects and m…

This study tests a new 'intelligent duvet' called Easy Sleep Monitoring (ESM) that uses built-in sensors to detect movement and estimate sleep. Researchers will compare its accuracy to standard sleep lab tests (video-polysomnography) in 50 people, including those with sleep disor…

This trial tests whether a structured therapeutic education program, delivered by general practitioners, can improve quality of life for people with heart failure. Around 200 patients in primary care will be randomly assigned to receive the program or usual care, and their qualit…

This study looks at how much people trust institutions (like health organizations) when it comes to advice about physical activity. Researchers will ask 2000 volunteers questions about their trust levels, lifestyle, and background. The goal is to understand what factors influence…

This study tests whether simple questionnaires can effectively measure quality of life in heart patients and job satisfaction in their caregivers. Over 1,100 participants from a French hospital will complete surveys before and after procedures like pacemaker insertion or heart su…

This study surveys 350 adults with hemophilia to better understand chronic pain—its type, location, and impact on daily life. Participants fill out questionnaires about their pain history, medication use, and emotional well-being. The goal is to help doctors recognize and treat p…

This study looks at how quickly risankizumab (Skyrizi) heals deep intestinal damage in people with Crohn's disease. Instead of repeated colonoscopies, researchers use intestinal ultrasound to track healing at 4 and 12 weeks. The goal is to find a simpler, more comfortable way to …

This study tests whether having a specialist give advice by phone during emergencies helps patients with severe bleeding who take blood thinners. About 1,000 patients will be treated either with standard care or with added expert guidance. Researchers will compare how well bleedi…

This study looks at how breast cancer itself may affect a woman's ability to have children later. Researchers are comparing egg quality and hormone responses in 100 women with breast cancer versus healthy egg donors. The goal is to understand why cancer can reduce the number and …

This study tests a tool called MSProgress that gives healthcare teams easy access to their own data, like how well they are doing on certain health measures. The tool is a simple 20-page report with 43 indicators that teams can choose from. The goal is to see if using this tool h…