New nasal spray could prevent migraines without drugs

NCT ID NCT07100496

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This trial tests a nasal spray called MIG-SPRAY for preventing migraines in 45 adults aged 18-55. The spray forms a protective film inside the nose to possibly stop migraine triggers. Participants use it three times daily for three months, and researchers track side effects and migraine frequency compared to a control group.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
MIG-SPRAY (a film-forming liquid nasal spray, classified as a medical device)
What this could lead to
If it works, this could offer a new, non-drug option for preventing migraines with fewer side effects.
What could go wrong
This is a small, early-phase trial focused on safety, not effectiveness. The device may not reduce migraines significantly, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MIGRAINE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Clermont-ferrand

    Clermont-Ferrand, 63000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.