Gut bug to heart threat: scientists investigate hidden path to deadly infection

NCT ID NCT07313865

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why a common gut bacterium, Enterococcus faecalis, sometimes travels to the heart and causes a serious infection called infective endocarditis. Researchers will analyze the gut bacteria of 90 adults with this bloodstream infection to see if an imbalance in the gut allows the bacteria to escape and infect heart valves. The goal is to find better ways to prevent this dangerous infection and its frequent relapses.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis Dysbiosis endocarditis Enterococcus faecalis infection infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, France, 63000, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact