Simple dental exam before heart surgery may prevent deadly infections

NCT ID NCT07511673

Recruiting now Prevention Sponsor: Region Skane Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether having a dental checkup before heart valve surgery can prevent serious complications like infection of the heart lining, repeat surgery, or death. About 1,300 adults scheduled for valve surgery will be randomly assigned to either get a dental screening or not. Researchers will then track their health for two years to see if the screening group has fewer problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: preoperative dental screening
What this could lead to: If it works, this could show that a simple dental exam before heart valve surgery reduces the risk of life-threatening infections and the need for repeat surgery.
What could go wrong: This is a large trial, but it's still possible that dental screening won't significantly improve outcomes. The study is open-label, so both patients and doctors know which group they're in, which could introduce bias.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endocarditis heart valve disorder infective endocarditis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART VALVE DISEASE INFECTIVE ENDOCARDITIS (IE)

Contacts and locations

Locations

Karolinska University Hospital
NOT_YET_RECRUITING

Stockholm, Sweden
Linköping University Hospital
NOT_YET_RECRUITING

Linköping, Sweden
Sahlgrenska University Hospital
NOT_YET_RECRUITING

Gothenburg, Sweden
Skane University Hospital
RECRUITING

Lund, Sweden
Örebro University Hospital
NOT_YET_RECRUITING

Örebro, Sweden

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