New nerve block could cut opioid use after heart surgery

NCT ID NCT07588230

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a specific nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and the need for opioid painkillers after minimally invasive heart valve surgery. 90 adults will be randomly assigned to receive either the nerve block with bupivacaine or a placebo before surgery. Researchers will measure total opioid use and pain scores in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If it works, this could offer a better way to manage pain after heart valve surgery, reducing the need for strong painkillers like opioids.
What could go wrong
This is a small, early-stage study. The nerve block may not provide significant pain relief, and there are risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart valve disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fatma Acil

    RECRUITING

    Diyarbakır, Outside of the US, 21070, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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