University Hospital, Bordeaux

This study is reviewing the results of using a drug called imlifidase for adult kidney transplant patients who are 'highly sensitized,' meaning their immune systems have developed many antibodies that make finding a compatible donor extremely difficult. The drug works by temporar…

This study aims to find out which of two surgical techniques works better for rebuilding large missing sections of bone in the leg. Researchers will observe 250 adult patients who have severe bone loss from trauma, infection, or tumor surgery. They will compare the traditional 'M…

This study aims to see if two less invasive procedures can control heavy menstrual bleeding and pain from adenomyosis as effectively as a hysterectomy. It will involve 230 women who are already candidates for a hysterectomy. Researchers will compare radiofrequency ablation (RFA) …

This study aims to see if giving pharmacists a special decision-support tool helps women with simple bladder infections make better choices about antibiotics. Currently, French rules often lead to automatic antibiotic prescriptions. The tool will guide a conversation about the pr…

This study is testing a new type of PET scan to see if it is better than current CT and MRI scans at finding out how far pancreatic or bile duct cancer has spread. The goal is to help doctors make more accurate treatment decisions from the start. The study will involve 120 patien…

This study is testing a new DNA analysis method called long-read sequencing to help diagnose rare genetic diseases. Researchers will use this advanced technology to examine DNA from 150 patients with unexplained intellectual disability or albinism who haven't received clear diagn…

This study aims to create and test a new tool to check the mouth health of adults in intensive care who are on breathing machines. The breathing tube can cause mouth sores and injuries, which can slow recovery. Researchers will test how well this new assessment tool works with 50…

This study tests whether having family doctors proactively give colon cancer screening kits to eligible patients improves participation rates. It compares this direct approach to the current system where people receive invitation letters in the mail. The goal is to find better wa…

This study aims to better understand how two types of benign adrenal tumors affect the body's daily hormone rhythms. Researchers will compare 40 patients with either a mildly hormone-producing tumor or a non-producing tumor. Using a special device that collects tiny fluid samples…

This study aims to understand why glioblastoma, an aggressive brain cancer, almost always returns after treatment. Researchers will collect tumor tissue and blood samples from 45 patients undergoing surgery to analyze the cancer's biology. The goal is to discover new targets for …

This study aims to understand how a specific type of cell death, called ferroptosis, is involved in systemic lupus erythematosus (SLE). Researchers will measure markers of this process in blood cells from 120 participants, including people with lupus and a control group with othe…

This study aims to understand if a rare genetic condition called Alpha-1 antitrypsin deficiency is linked to liver cancer in patients who developed the cancer without cirrhosis or other known risk factors. Researchers will look back at medical data from 71 patients in France who …

This study aims to better understand how congenital heart disease affects brain blood flow in babies. Researchers will use a new, non-invasive ultrasound technique to monitor 300 infants under age 2 who are hospitalized for heart surgery. The goal is to gather information that co…

This study will follow children and their mothers for five years to understand the long-term effects of two different approaches to late pregnancy. It compares inducing labor at 39 weeks of pregnancy to waiting for labor to start naturally in first-time, low-risk mothers. The mai…

This study aims to find early warning signs for liver cancer in people with a serious form of fatty liver disease called MASH. Researchers will look back at old liver biopsy samples from 30 patients—15 who later got liver cancer and 15 who didn't—to see if specific protein patter…

This study aims to understand how certain harmful compounds, called AGEs, build up in the bodies of adults and children who need to get their nutrition through a vein for a long time. Researchers will use a simple, non-invasive skin scanner to measure these compounds over 12 mont…

This study aims to understand a serious and often fatal complication of Q fever, a disease people can get from animals. Researchers will look back at the medical records of 400 adults in France who had infections in their blood vessels caused by the Q fever bacteria. The goal is …

This study aims to understand why some adults with Common Variable Immunodeficiency (CVID) develop serious non-infectious complications while others don't. Researchers will examine specific immune cells called Tph cells in 60 participants to see if these cells help drive harmful …

This study aims to see if a new computer method is as good as the current expert-led method for finding tiny amounts of leftover leukemia cells after treatment. Researchers will look back at lab results from 60 patients (50 adults and 10 children) with acute myeloid leukemia. The…

This study aims to understand if a person's psychological state and social background are connected to their spinal posture, even when they have no back disease. Researchers will collect X-ray images and questionnaire answers from 150 adults with healthy spines. The goal is to ga…

This study aims to better understand why people with Noonan syndrome often bleed more easily. Researchers will look at data from 100 patients to see if standard medical tests can reliably predict who is at high risk for serious bleeding, especially before surgery. The goal is to …

This study looks back at 10 years of medical records from 12 French hospitals to learn about rare but serious fungal infections that occur on artificial blood vessels (vascular grafts). Researchers will analyze 300 past cases to understand how these infections happened, how they …

This study aims to understand the link between fatigue and physical fitness in children, teens, and young adults (ages 8-25) living with chronic immune thrombocytopenic purpura (ITP), a blood disorder. Researchers will measure participants' aerobic fitness and compare it to their…

This study aims to understand if damage to a specific thigh muscle during hip replacement surgery affects how well patients recover in the short term. Researchers will observe 150 adults getting hip replacements through a specific surgical approach, grading any muscle damage seen…