Could a simple scalp injection replace opioids after brain surgery?
NCT ID NCT07149077
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether adding ultrasound-guided scalp blocks—local anesthetic injections around the scalp—to standard anesthesia can reduce severe pain after planned brain surgery. Up to 30% of patients experience moderate to severe pain after such procedures, and current painkillers often rely heavily on opioids. The study will compare the need for morphine and pain scores in the first six hours after surgery between patients receiving the blocks and those receiving standard care alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Echo-guided scalp blocks (local anesthetic injections around the scalp nerves) added to standard anesthesia
- What this could lead to
- If effective, this approach could offer a safer way to manage pain after brain surgery, reducing opioid use and related complications.
- What could go wrong
- The trial is still in progress, and results may not confirm a benefit. Scalp blocks carry small risks like bleeding or infection, and their effectiveness can vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bordeaux university hospital
Bordeaux, France
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Other studies related to the condition(s) this trial covers.
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