Could a simple scalp injection replace opioids after brain surgery?

NCT ID NCT07149077

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial tests whether adding ultrasound-guided scalp blocks—local anesthetic injections around the scalp—to standard anesthesia can reduce severe pain after planned brain surgery. Up to 30% of patients experience moderate to severe pain after such procedures, and current painkillers often rely heavily on opioids. The study will compare the need for morphine and pain scores in the first six hours after surgery between patients receiving the blocks and those receiving standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Echo-guided scalp blocks (local anesthetic injections around the scalp nerves) added to standard anesthesia
What this could lead to
If effective, this approach could offer a safer way to manage pain after brain surgery, reducing opioid use and related complications.
What could go wrong
The trial is still in progress, and results may not confirm a benefit. Scalp blocks carry small risks like bleeding or infection, and their effectiveness can vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bordeaux university hospital

    Bordeaux, France

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Other studies related to the condition(s) this trial covers.