Spinal canal shape may hold key to Chiari-Related syringomyelia

NCT ID NCT07720206

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By invitation only
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Paused for now. It may or may not start again.
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Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study uses advanced MRI to examine whether a deformity in the upper spinal canal is linked to syringomyelia (fluid-filled cavities in the spinal cord) in people with Chiari malformation type I. Researchers will compare MRI scans from 50 adults with Chiari malformation, with or without syringomyelia, to measure the shape of the central spinal canal. The goal is to better understand the connection between these two conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, it could improve understanding of how syringomyelia develops in Chiari malformation, potentially guiding future treatments.
What could go wrong
This is an observational imaging study, not a treatment trial. It may not lead to direct clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients being treated for Chiari malformation or syringomyelia at Bordeaux University Hospital * Patients admitted for an initial surgical consultation regarding Chiari malformation with or without syringomyelia at Bordeaux University Hospital * Individuals enrolled in or covered by a social security program. * Free, informed, and express consent (confirmed in writing) (no later than the day of enrollment and prior to any examination required by the study). Exclusion Criteria: * Pregnant or breastfeeding patients * Contraindications to MRI * Individuals deprived of their liberty by judicial or administrative order, * Adults subject to legal protective measures (guardianship, conservatorship, judicial protection). * Patients who have previously undergone surgery for a Chiari malformation or a posterior fossa malformation

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Bordeaux university hospital

    Bordeaux, France

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