Spinal canal shape may hold key to Chiari-Related syringomyelia
NCT ID NCT07720206
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This study uses advanced MRI to examine whether a deformity in the upper spinal canal is linked to syringomyelia (fluid-filled cavities in the spinal cord) in people with Chiari malformation type I. Researchers will compare MRI scans from 50 adults with Chiari malformation, with or without syringomyelia, to measure the shape of the central spinal canal. The goal is to better understand the connection between these two conditions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could improve understanding of how syringomyelia develops in Chiari malformation, potentially guiding future treatments.
- What could go wrong
- This is an observational imaging study, not a treatment trial. It may not lead to direct clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients being treated for Chiari malformation or syringomyelia at Bordeaux University Hospital * Patients admitted for an initial surgical consultation regarding Chiari malformation with or without syringomyelia at Bordeaux University Hospital * Individuals enrolled in or covered by a social security program. * Free, informed, and express consent (confirmed in writing) (no later than the day of enrollment and prior to any examination required by the study). Exclusion Criteria: * Pregnant or breastfeeding patients * Contraindications to MRI * Individuals deprived of their liberty by judicial or administrative order, * Adults subject to legal protective measures (guardianship, conservatorship, judicial protection). * Patients who have previously undergone surgery for a Chiari malformation or a posterior fossa malformation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bordeaux university hospital
Bordeaux, France
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