University Hospital, Bordeaux

This study is for people with rheumatoid arthritis (RA) who haven't gotten enough relief from their current biologic or targeted drugs. It's testing if taking two powerful medications together—baricitinib and an anti-TNF drug—works better to control the disease than taking just b…

This study aims to find the best treatment approach for patients with non-small cell lung cancer that has spread to the brain in a limited way (fewer than 5 spots). Researchers are comparing two strategies: treating the main tumor and brain spots directly versus using body-wide m…

This study is testing if adding the common diabetes medication metformin to the standard first-line arthritis drug methotrexate works better for controlling rheumatoid arthritis. It will involve 128 adults with active rheumatoid arthritis who are starting methotrexate treatment. …

This study is testing whether combining two drugs, spartalizumab and pazopanib, can help control advanced solid tumors that have come back or stopped responding to standard treatments. It will enroll about 80 children and adults to find the safest dose for kids and see if the com…

This study is testing whether virtual reality (VR) therapy can help people feel better about their bodies after they have had major weight loss (bariatric) surgery. It compares a special VR program designed to help patients accept their new body shape against the standard follow-…

This study aims to find better ways to identify which people with lupus are most likely to develop heart disease. Researchers will follow 500 adult lupus patients, measuring specific substances in their blood and using ultrasound to track artery health over time. The goal is to d…

This study uses French national health insurance data to see if routinely screening for hidden heart disease helps prevent major heart problems in people with type 2 diabetes who are at very high risk. It will compare the health outcomes and costs for about 90,000 patients who we…

This study aims to understand why some organ transplant patients develop severe, hard-to-treat Cytomegalovirus (CMV) infections. Researchers are collecting blood samples and health data from over 550 transplant patients across Europe. By studying these samples, they hope to ident…

This study aims to understand how and why thinking and memory problems develop in people with primary progressive multiple sclerosis (PPMS). Researchers are following 66 patients for two years, using detailed brain scans and cognitive tests to see how brain changes relate to chan…