Unity Health Toronto

This study is testing whether virtual education and support can help adults with type 1 diabetes better manage their condition. Participants will receive frequent, brief video check-ins with diabetes educators and access to online resources, alongside their regular clinic visits.…

This study is testing whether a lower total dose of the standard emergency drug epinephrine (adrenaline) leads to better survival for adults who suffer a specific type of cardiac arrest outside the hospital. Paramedics will randomly give eligible patients either the lower dose or…

This study is testing whether a special light therapy headset can help people with early memory loss from Alzheimer's disease. About 60 participants will use the device, which shines safe, near-infrared light into the brain, for 12 weeks. Researchers want to see if it's safe, eas…

This study aims to find the best surgical treatment for hip socket fractures in people aged 60 and older. It will compare two common surgeries: one that fixes the bone with plates and screws, and another that combines that repair with a total hip replacement. Researchers will fol…

This study is testing whether customizing ventilator settings based on detailed measurements of a patient's lung function can help more people survive severe lung failure (ARDS). It will compare this personalized approach to standard ventilator care in 740 critically ill patients…

This study aims to find the better surgery for knee fractures in people 65 and older who already have a knee replacement. Researchers will compare fixing the broken bone with plates and screws to replacing the joint with a new artificial knee. The main goal is to see which surger…

This study is testing whether providing vouchers for healthy foods helps people with type 2 diabetes or prediabetes who struggle financially to better control their blood sugar. Researchers will give 390 low-income participants either food vouchers or standard care and track thei…

This study is testing a new at-home kit that checks for HIV and syphilis from a finger-prick of blood. Researchers want to see if people with no medical training can use it correctly and get accurate results. The study involves 900 people in Canada who are getting tested for thes…

This pilot study is testing a comprehensive support program for young adults (ages 18-24) who are transitioning out of homelessness in Ontario. The program provides job placement, housing funds, groceries, coaching, and life skills training over 18 months. The main goal is to see…

This study is testing if a steroid injection in the knee that is NOT being replaced can help people recover better from total knee replacement surgery. Researchers want to see if reducing pain in the 'good' knee helps patients move more easily and feel less overall pain after the…

This study is testing a new 12-week therapy program designed to reduce suicide risk in adults who experienced childhood trauma and currently have suicidal thoughts. The therapy combines suicide prevention skills training with trauma-focused treatment. Researchers are enrolling 20…

This study is testing whether a single therapy session called 'Brief Skills for Safer Living' can help reduce suicidal thoughts and improve mental health. Researchers will compare 150 Canadian adults who receive the therapy immediately against those who wait three months. The goa…

This small pilot study is testing whether MDMA (commonly known as ecstasy), combined with psychotherapy, can help people with severe, treatment-resistant nerve pain. Forty adults with long-term, debilitating pain will receive either MDMA or an active placebo during a guided thera…

This study is testing a new digital platform called the Genetics Navigator. It's designed to help guide patients and parents through the complex process of genetic testing for conditions like cancer, heart disease, and epilepsy. Researchers want to see if using this online tool r…

This study aims to understand why some people with depression don't respond to standard medications by comparing brain scans of three groups: people with treatment-resistant depression, people whose depression responds to medication, and healthy individuals. Researchers will use …

This study aims to understand how a medical device used to hold an open surgical wound together affects patients' breathing. Researchers will measure lung pressure, volume, and oxygen levels in 18 sedated ICU patients before and after adjusting the device. The goal is to see if c…