Knee replacement may offer faster recovery for seniors with thigh fractures

NCT ID NCT04076735

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgeries for a broken thigh bone near the knee in people aged 65 and older: replacing the damaged knee with an artificial joint (distal femoral replacement) or fixing the bone with plates and screws (ORIF). The goal is to see which approach leads to better function, less pain, and fewer complications. 140 participants will be randomly assigned to one of the two procedures and followed for a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Distal femoral replacement (artificial knee) or surgical fixation with plates/screws
What this could lead to
If it works, this could show that knee replacement allows faster recovery and fewer complications than standard fixation for older adults with a broken thigh bone.
What could go wrong
This is a relatively small trial (140 people) and results may not apply to all patients. Both procedures carry risks like infection or implant failure, and the best option may depend on individual health.

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Conditions

The condition(s) this trial relates to.

Femoral Fractures, Distal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St Michael's Hospital - Unity Health Toronto

    RECRUITING

    Toronto, Ontario, Canada

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