Which surgery restores mobility best after a knee fracture?

NCT ID NCT05792189

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study looks at two surgical options for fractures of the lower thigh bone near the knee: open reduction internal fixation (ORIF), which uses plates and screws, and distal femur replacement (DFR), which replaces the damaged bone with an artificial joint. The trial enrolls adults 55 and older with these fractures, including those with a previous knee replacement. Researchers will compare how well patients recover by measuring mobility with a timed walking test and knee function using a patient questionnaire. The goal is to find out which approach leads to better recovery and fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Two surgical procedures: open reduction internal fixation (ORIF) and distal femur replacement (DFR)
What this could lead to
If this trial succeeds, it could help surgeons choose the best surgical method for distal femur fractures, potentially improving mobility and quality of life for patients.
What could go wrong
This is a non-randomized observational study, so results may be influenced by patient differences. Surgical risks include infection, implant failure, and complications from anesthesia.

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Conditions

The condition(s) this trial relates to.

Femoral Fractures, Distal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UF & Shands Orthopaedics and Sports Medicine Institute

    RECRUITING

    Gainesville, Florida, 32607, United States

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