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New ventilator strategy aims to save lives in severe lung failure

NCT ID NCT03963622

Recruiting now Disease control Sponsor: Unity Health Toronto Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether setting a breathing machine based on each patient's lung mechanics can lower the chance of death within 60 days for people with acute respiratory distress syndrome (ARDS). It includes both COVID-19 and non-COVID-19 patients. The approach is compared to standard ventilation care.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome COVID-19 Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARDS

Contacts and locations

Locations

  • Arcispedale Sant'Anna

    RECRUITING

    Ferrara, Italy

  • CH Bretagne Atlantique Vannes-Auray

    RECRUITING

    Vannes, France

  • CH Victor Dupouy

    RECRUITING

    Argenteuil, France

  • CH de Beauvais

    RECRUITING

    Beauvais, France

  • CH de Cholet

    RECRUITING

    Cholet, France

  • CHU Amiens-Picardie

    RECRUITING

    Amiens, France

  • CHU Bordeaux - Haut Leveque

    RECRUITING

    Bordeaux, France

  • CHU Grenoble-Alpes

    RECRUITING

    Grenoble, France

  • CHU de Poitiers - La Miletrie

    RECRUITING

    Poitiers, France

  • Centre hospitalier universitaire d'Angers

    RECRUITING

    Angers, France

  • Centro de Educación Médica e Investigaciones Clínicas Dr Norberto Quirno (CEMIC)

    RECRUITING

    Buenos Aires, Argentina

  • Complejo Médico Policía Federal Argentina Churruca Visca

    RECRUITING

    Buenos Aires, Argentina

  • Groupe Hospitalier de la Region de Mulhouse et Sud Alsace

    RECRUITING

    Mulhouse, France

  • HIA Robert Picque

    RECRUITING

    Villenave-d'Ornon, France

  • Hopital Europeen Georges-Pompidou

    RECRUITING

    Paris, France

  • Hopital Intercommunal de Creteil

    RECRUITING

    Créteil, France

  • Hopital Roger Salengro - CHU Lille

    RECRUITING

    Lille, France

  • Hopital de l'Archet 1 - CHU de Nice

    RECRUITING

    Nice, France

  • Hopital de la Cavale Blanche - CHRU Brest

    RECRUITING

    Brest, France

  • Hospital Británico de Buenos Aires

    RECRUITING

    Buenos Aires, Argentina

  • L'Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, Spain

  • New York University Grossman School of Medicine

    RECRUITING

    New York, New York, 10016, United States

  • OLVG

    RECRUITING

    Amsterdam, North Holland, Netherlands

  • Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Rome, Italy

  • Pontificia Universidad Católica de Chile

    RECRUITING

    Santiago, Chile

  • Sanatorio Anchorena Recoleta

    RECRUITING

    Buenos Aires, Argentina

  • Sanatorio Anchorena San Martín

    RECRUITING

    San Martin, Argentina

  • Sanatorio Mater Dei

    RECRUITING

    Buenos Aires, Argentina

  • St. Michael's Hospital

    RECRUITING

    Toronto, Canada

  • Toronto General Hospital

    RECRUITING

    Toronto, Canada

  • Toronto Western Hospital

    RECRUITING

    Toronto, Canada

  • University of Foggia

    RECRUITING

    Foggia, Italy

  • Vall d'Hebron University Hospital

    RECRUITING

    Barcelona, Spain

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