Could whole blood save more trauma patients? new canadian trial aims to find out
NCT ID NCT06495294
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether giving trauma patients whole blood instead of separate red blood cells and plasma before reaching the hospital is feasible and improves outcomes. About 60 adults with severe traumatic bleeding will be randomly assigned to receive either two units of whole blood or four units of blood components. The study focuses on whether paramedics can successfully give the assigned blood and collect complete data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Whole blood
- What this could lead to
- If this approach works, it could simplify prehospital care and improve survival for trauma patients with severe bleeding.
- What could go wrong
- This is a small pilot study (60 participants) focused on feasibility, not yet on proving better outcomes. Results may not apply broadly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TRAUMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ornge Air Ambulance
RECRUITINGToronto, Ontario, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- What did COVID-19 mean for family caregivers in zambia? a study seeks answers
- Can early blood transfusions save more trauma victims?
- Lab-Grown blood vessels could save limbs after trauma
- Hormone patch may reveal why some women develop PTSD after trauma
- Can a light camera see bacteria on broken bones?
- Stent graft aims to fix aortic arch without open surgery