Could whole blood save more trauma patients? new canadian trial aims to find out

NCT ID NCT06495294

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether giving trauma patients whole blood instead of separate red blood cells and plasma before reaching the hospital is feasible and improves outcomes. About 60 adults with severe traumatic bleeding will be randomly assigned to receive either two units of whole blood or four units of blood components. The study focuses on whether paramedics can successfully give the assigned blood and collect complete data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Whole blood

What this could lead to

If this approach works, it could simplify prehospital care and improve survival for trauma patients with severe bleeding.

What could go wrong

This is a small pilot study (60 participants) focused on feasibility, not yet on proving better outcomes. Results may not apply broadly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ornge Air Ambulance

    RECRUITING

    Toronto, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact