Unity Health Toronto
Clinical trials sponsored by Unity Health Toronto, explained in plain language.
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Can therapy make a pain drug last longer?
Symptom relief CompletedThis small, completed study explored whether adding psychotherapy to ketamine treatment helps make pain relief last longer for people with chronic nerve pain. Thirty adults with moderate-to-severe nerve pain were randomly assigned to receive either ketamine, psychotherapy, or a c…
Phase: PHASE4 • Sponsor: Unity Health Toronto • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Could laughing gas lift your mood? brain scan study investigates
Symptom relief CompletedThis small pilot study looked at whether inhaling nitrous oxide (laughing gas) could improve symptoms of major depression. Researchers used brain scans (MRIs) to see if the treatment changed brain activity and connections in 11 participants. They compared the effects of laughing …
Sponsor: Unity Health Toronto • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Heart surgery pain breakthrough? local block could slash opioid need
Symptom relief CompletedThis study tested whether a local anesthetic block, given through small tubes near the breastbone, could reduce the need for strong opioid painkillers after open-heart surgery. Researchers compared the anesthetic to a saltwater placebo in 340 patients. The main goal was to see if…
Phase: NA • Sponsor: Unity Health Toronto • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Can a leadership program help youth build a new life after homelessness?
Knowledge-focused CompletedThis study tested a 4-week, in-person leadership program designed for young people (ages 16-24) who had recently left homelessness. The main goal was to see if participants liked the program and found it useful. Researchers also checked if the program helped improve participants'…
Phase: NA • Sponsor: Unity Health Toronto • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Scientists search for Brain's suicide warning signs
Knowledge-focused CompletedThis study aimed to find biological markers, or signs, that could help predict suicide risk in people with major depression. Researchers used brain scans, thinking tests, and behavioral tasks to measure how people process pain, reward, and attention. They followed 97 adults with …
Sponsor: Unity Health Toronto • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC