Unity Health Toronto

This small pilot study tested the safety and effectiveness of the oral drug sirolimus for reducing nosebleeds in people with hereditary hemorrhagic telangiectasia (HHT). Ten adults with moderate to severe nosebleeds took 2 mg of sirolimus daily for 3 months. Researchers tracked b…

This pilot study tested whether adding cognitive behavioral therapy and mindfulness meditation to ketamine infusions could make pain relief last longer for people with chronic nerve pain. Thirty adults with moderate-to-severe neuropathic pain were randomly assigned to receive ket…

This small pilot study tested whether laughing gas (nitrous oxide) can improve mood in people with major depressive disorder. Eleven participants received either laughing gas or a sedative (midazolam), and researchers used brain scans to look for changes in brain activity. The go…

This study tested whether a nerve block placed near the breastbone after heart surgery can reduce the need for opioid painkillers. 340 adults having heart surgery through a standard chest incision were randomly assigned to receive either the numbing drug ropivacaine or a saltwate…

This study tested whether one-on-one support from a resource navigator helps long-term care and retirement home staff access health and wellness resources. 123 staff members took part, with some getting a navigator and others not. Researchers measured changes in wellness, burnout…

This pilot study gave 40 young people (ages 16-24) leaving homelessness a rent subsidy for 12 months. Half also received a coach and a guided workbook to build confidence and life skills. The goal was to see if this combined support is practical and helps with housing, school, or…

This study tested whether a navigator program, where a Homeless Outreach Counsellor helps patients follow their discharge plan and connect with community services, improves outcomes for homeless adults after a hospital stay. Over 650 participants were randomly assigned to receive…

This completed trial tested whether a community health surveyor could help collect social and demographic information from adult primary care patients who are hard to reach due to factors like low income or housing instability. About 760 patients were assigned to either usual car…

This study looked at over 2,200 people with hereditary hemorrhagic telangiectasia (HHT), a rare condition that causes abnormal blood vessels. The goal was to find out what makes some people with HHT more likely to have a brain bleed. Researchers collected health information, bloo…

This completed study looked for biological markers of suicide risk in 97 adults with major depressive disorder. Researchers used brain scans to measure how participants respond to pain, reward, and attention. The goal was to find stable brain-based signs that could help identify …

This study tested a four-week, in-person leadership program for young people aged 16-24 who have recently left homelessness. The program was co-designed with youth and coaches to build strengths and identity capital—like a sense of purpose and confidence. Researchers measured how…