Cheap Blood-Clot drug could cut repeat brain surgery risk
NCT ID NCT05713630
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether tranexamic acid (TXA), a cheap drug that prevents blood clots from breaking down, can help people recover from a subdural hematoma—a collection of blood on the brain after a head injury. About 130 adults aged 45 and older with symptoms like headache or confusion will be randomly assigned to receive TXA or a placebo. Researchers will track quality of life, bleeding, and recovery over time to see if TXA reduces the need for repeat surgery and speeds healing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid (TXA)
What this could lead to
If it works, this could provide a cheap, widely available drug to reduce repeat bleeding and speed recovery after a subdural hematoma, potentially lowering the need for additional surgeries.
What could go wrong
This is a mid-stage trial with only 130 participants, so results may not apply to everyone. TXA can rarely cause blood clots or allergic reactions, and the drug may not prove better than placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St. Michael's Hospital
RECRUITINGToronto, Ontario, M5B1T8, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••