Why Won't depression go away? scientists scan brains for answers

NCT ID NCT03537794

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand why some people with depression don't get better with standard medications. Researchers will use brain scans to compare dopamine receptors in 45 people: those with treatment-resistant depression, those whose depression responds to treatment, and healthy volunteers. The goal is to find biological differences that could lead to better treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Unity Health Toronto

    RECRUITING

    Toronto, Ontario, M5B 1M4, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.