The Children's Hospital Of Zhejiang University School Of Medicine

This study aims to see if using a child's genetic information to decide the dose of a chemotherapy drug (6-MP) can lower the risk of dangerous low white blood cell counts and infections. About 110 children with acute lymphoblastic leukemia will receive a personalized dose based o…

This study tests a 12-week family-empowered pulmonary rehabilitation program for children aged 6-12 with asthma. The goal is to see if this home-based approach improves asthma control and lung function better than standard care. About 92 children and their families will participa…

This study tests a new drug called Telitacicept in 30 children with ocular myasthenia gravis, a condition that causes eye muscle weakness and double vision. The goal is to see if the drug can better control symptoms and reduce the need for steroids, which have harsh side effects.…

This study looks at whether a drug called telitacicept can help children aged 3-17 with kidney inflammation caused by IgA vasculitis. The goal is to see if it works better than standard steroid treatment at reducing protein in the urine and protecting kidney function. About 300 c…

This study looks at whether giving children with Crohn's disease a combination of two drugs (infliximab and azathioprine) works better than infliximab alone. About 154 children with moderate to severe Crohn's will take part. The goal is to see which approach leads to higher remis…

This study tests a new surgical technique (urethral plate flap) against a standard method (tunica vaginalis flap) for correcting severe penile curvature in children with hypospadias. About 90 boys aged 6 months to 14 years will take part. The goal is to see if the new method work…

This study aims to find the optimal timing for a procedure called bronchoscopic lung lavage in children with severe pneumonia. About 3,168 children will be enrolled to see if earlier or later intervention improves breathing support success, reduces hospital stay, and lowers costs…

This study looks at the best way to feed very premature babies (born before 29 weeks) when their mother's milk isn't enough. It compares donor human milk versus special formula, and also tests whether adding extra nutrients to milk should be routine or only when growth is slow. T…

This study tests whether giving the medicine lidocaine during heart surgery can reduce lung damage in babies under 1 year old. Lung injury is a common problem after infant heart surgery, leading to longer time on breathing machines and in the ICU. The trial will compare lidocaine…

This study will test whether an artificial intelligence (AI) system can accurately diagnose inherited metabolic disorders in newborns during routine screening. Researchers will compare the AI's results to standard manual interpretation by trained staff. The goal is to see if the …

This study looks at whether a blood test for a substance called copeptin can help doctors diagnose and classify bedwetting in children aged 5 to 18. Currently, diagnosis relies on a detailed urine diary, which is often inaccurate and inconvenient. The goal is to find a simpler, m…

This study tests two different ways of giving the steroid dexamethasone to very premature babies (born at 24-29 weeks) who need a breathing machine. The goal is to see which method better prevents bronchopulmonary dysplasia (BPD), a serious chronic lung disease, or death. About 9…

This study tests a program to help girls aged 9-17 and their parents feel more confident about the HPV vaccine, which prevents certain cancers. The program includes easy-to-understand materials, doctor support, and reminders. Researchers will see if more girls get the vaccine wit…

This study tests whether inhaling a gas called xenon for 10 minutes each day can improve social skills in children with autism. 72 children aged 4-18 will receive either xenon or a placebo gas for 10 days. Researchers will check for changes in social behavior and safety right aft…

This study tests a new camera system that helps doctors locate kidney stones in children more quickly during shock wave treatment. About 80 children will be randomly assigned to either the standard ultrasound method or the new camera-assisted method. The goal is to see if the cam…

This study will follow 400 children and teens who have survived blood cancers like leukemia and lymphoma. Researchers want to understand the long-term health problems these survivors face and create a structured follow-up plan using an electronic platform. The goal is to improve …

This study follows 330 infants aged 0-6 months with congenital hydronephrosis (a common kidney condition) over 3 years to see how it naturally progresses or resolves. Researchers will use ultrasounds to track changes and identify factors that influence outcomes. The goal is to pr…

This study looks at why some young children get severe tooth decay that keeps coming back. Instead of only looking at teeth, researchers will also study family stress, children's behavior, and sleep patterns. They plan to collect data from 1,200 preschool children and their paren…