The Children's Hospital Of Zhejiang University School Of Medicine

This study aims to find the best time to perform a bronchoscopy, a procedure to wash out the lungs, in children with severe pneumonia. Researchers will compare giving the procedure early (within 24 hours), later (within 72 hours), or not at all, alongside standard medical care. T…

This study aims to find out if giving two drugs together (infliximab and azathioprine) works better and is as safe as giving just one drug (infliximab) for children with active Crohn's disease. Researchers will compare how well each treatment reduces gut inflammation and controls…

This study aims to see if breathing a gas called xenon can help improve social skills in children with autism. Children aged 4-18 will breathe either xenon or a placebo gas for 10 minutes a day over 10 days. Researchers will measure changes in social behavior and check the treatm…

This study compares two surgical techniques for correcting severe penile curvature in children with hypospadias, a birth defect. Researchers want to see if a new method using tissue from the penis itself works as well as the standard method using tissue from the scrotum, but with…

This study is testing a new approach to dosing a common leukemia drug called 6-MP for children. Researchers will use genetic test results to personalize the starting dose for each child during long-term maintenance therapy. The goal is to see if this gene-guided dosing can reduce…

This study aims to find the safest and most effective steroid treatment to prevent a serious lung condition called bronchopulmonary dysplasia (BPD) in very premature infants. It will compare two different dosing schedules of the steroid dexamethasone in about 970 babies born extr…

This study aims to see if a drug called telitacicept is a safe and effective treatment for kidney inflammation in children with IgA vasculitis, a condition that can lead to long-term kidney damage. It will compare telitacicept to standard steroid treatments in about 300 children …

This large study aims to find the best feeding plan for very premature babies born before 29 weeks. It will compare using donor breast milk versus special formula when a mother's own milk is not enough, and test different ways of adding nutrients to breast milk. The goal is to re…

This study is testing a medication called Telitacicept in children with ocular myasthenia gravis, a condition that causes eye muscle weakness. The goal is to see if this treatment can better control symptoms and reduce the need for steroids, which often cause side effects. Resear…

This study is testing a new computer-assisted system designed to help doctors find and target kidney stones more quickly and easily in children. The goal is to make a common non-surgical stone-breaking treatment faster and less dependent on a doctor's experience. Researchers will…

This study aims to see if a blood test measuring a hormone called copeptin can help doctors better diagnose and classify bedwetting in children. Researchers will compare blood levels in 180 children with bedwetting to healthy volunteers. The goal is to find a simpler, more object…

This study aims to test a new computer system that uses artificial intelligence (AI) to read newborn screening blood tests. It will check if the AI is as good as human experts at finding rare inherited metabolic disorders in babies. Researchers will compare the AI's results with …

This study aims to understand how congenital hydronephrosis (swelling in a baby's kidney) naturally changes over the first three years of life. Researchers will follow 330 infants diagnosed before six months old, tracking whether the condition gets better, stays the same, or wors…

This study aims to create and test a structured follow-up system for children and young adults who have survived blood cancers like leukemia and lymphoma. It will track 400 survivors for three years to understand the long-term health problems they face and see if a new, organized…

This study aims to understand why some young children get severe cavities by looking beyond just diet and bacteria. Researchers will collect information from 1,200 children and their parents about family stress, kids' sleep, screen time, and behavior to find patterns. The goal is…