Could donor milk save tiny babies from deadly gut disease?
NCT ID NCT07045844
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This large trial studies over 2,300 very preterm infants (born before 29 weeks) to see whether supplementing mother's milk with pasteurized donor milk or preterm formula improves survival without severe necrotizing enterocolitis (NEC), a dangerous gut condition. It also tests whether routine use of human milk fortifiers is better than using them only when growth slows. Infants are randomly assigned to feeding groups, and their development is checked at age 2.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pasteurized donor human milk and preterm formula
What this could lead to
If successful, this could identify the best feeding strategy to help very preterm infants survive without severe gut complications and support better brain development.
What could go wrong
This is an early-stage trial with no results yet. The benefits may be small or not apply to all infants, and feeding interventions carry risks like infection or intolerance.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 0571, China
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Ganzhou Maternal and Child Health Hospital
Ganzhou, Jiangxi, China
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Hangzhou Women's Hospital
Hangzhou, Zhejiang, 310008, China
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Jiaxing Maternity and Child Health Care Hospital
Jiaxing, Zhejiang, 314000, China
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Nanyang Central Hospital
Nanyang, Henan, 473000, China
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Ningbo Women and Children's Hospital (The Affiliated Women and Children's Hospital of Ningbo University)
Ningbo, Zhejiang, 315012, China
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Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital)
Yinchuan, Ningxia, China
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People's Hospital of Xinjiang Uygur Autonomous Region
Ürümqi, Xinjiang Uygur Autonomous Region, China
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Shandong Provincial Maternal and Child Health Care Hospital
Jinan, Shandong, China
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Sichuan Provincial Maternal and Child Health Hospital
Chengdu, Sichuan, 610045, China
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310016, China
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The Affiliated Hospital of Guizhou Medical University
Guizhou, Guiyang, 550001, China
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The Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, China
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The First Affiliated Hospital of Guilin Medical University
Guilin, Guangxi, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
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The Second Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, 530007, China
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Women's Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310006, China
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Yiwu Maternity and Child Health Care Hospital (Yiwu Branch of The Children's Hospital, Zhejiang University School of Medicine)
Yiwu, Zhejiang, 322000, China
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Yiyang Central Hospital
Yiyang, Hunan, China
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Yongkang Maternity and Child Health Care Hospital
Guli, Zhejiang, 321300, China
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Yulin Maternity and Child Health Care Hospital, Guangxi
Yulin, Guangxi, 537000, China
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