The Children's Hospital Of Zhejiang University School Of Medicine

This early-stage study is testing a new cell therapy called CAR-NK for children with severe rheumatic diseases that haven't responded to standard treatments. Doctors will give a single infusion of these specially modified immune cells to see if it's safe and can help put the dise…

This early-stage study is testing a new cell therapy for children with severe autoimmune diseases that haven't responded to standard treatments. Researchers are modifying a patient's own natural killer (NK) immune cells to target and remove harmful B cells that drive the disease.…

This study is testing a new, one-time gene therapy called EXG110 for people with Fabry disease, a rare genetic disorder. Researchers want to find a safe dose and see if it can help control the disease by improving kidney and heart function. The study is enrolling a small group of…

This study aims to see if a detailed blood test that maps a child's specific dust mite allergies can help doctors predict how well standard allergy shots will work. Researchers will follow 1,000 children in China, aged 5-18, who are already getting these shots as part of their re…

This early-stage study is testing the safety and initial effects of a new type of cell therapy for people with severe autoimmune diseases that haven't responded well to standard treatments. The therapy, called 'universal' CAR-T, uses donated immune cells engineered to target and …

This is a very early study testing a new type of cell therapy for children with severe autoimmune diseases like lupus and scleroderma that haven't improved with standard treatments. Doctors will collect a patient's own immune cells, modify them in a lab to better target the disea…

This early-stage study is testing whether a therapy called CAR-T, which reprograms a patient's own immune cells, can help people with severe systemic sclerosis (scleroderma) that hasn't responded to other treatments. The goal is to see if this approach is safe and can reduce skin…

This early-stage study is testing a new, quickly manufactured cell therapy for people with severe lupus that hasn't responded to standard drugs. Doctors take a patient's own immune cells, modify them to target harmful B cells thought to drive lupus, and infuse them back. The main…

This study is testing whether a special type of ultrasound, which uses a safe contrast agent, can help doctors more accurately diagnose abdominal issues in children. It involves children from 29 days to 18 years old who have suspected tumors, injuries, or unexplained fluid in the…

This study aims to understand how the immune system changes in children with severe, hard-to-treat lupus who are already receiving a specific therapy that targets B cells. Researchers will collect blood samples from 6 participants over time to analyze immune cells and see how the…

This study aims to understand why many childhood cancer survivors continue to experience groups of symptoms like fatigue, pain, and depression. Researchers will follow 600 survivors and their caregivers, collecting surveys and stool samples over time. The goal is to see if change…