Could CAR-T therapy ease severe skin tightening in sclerosis?
NCT ID NCT06792344
First seen Jan 05, 2026 · Last updated Jun 08, 2026 · Updated 25 times
Summary
This early-phase study tests whether a type of immune cell therapy called CAR-T can safely help people with severe systemic sclerosis that hasn't responded to standard treatments. The therapy targets CD19 on immune cells to reduce disease activity. Up to 12 participants aged 5 and older will receive the treatment and be monitored for changes in skin thickness and other symptoms over 6 to 12 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 0571, China
Contact
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Children's Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310053, Christmas Island
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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