The Children's Hospital Of Zhejiang University School Of Medicine

This early-stage study is testing a new treatment for autoimmune diseases like lupus, kidney disease, and scleroderma. It uses specially engineered immune cells (CAR T-cells) from a healthy donor to target and calm the overactive immune system. The main goal is to check safety an…

This study tests a new gene therapy, EXG110, for people with Fabry disease, a rare genetic condition. The goal is to see if it is safe and can help control the disease. About 12 people aged 7 and older will receive a single dose of the therapy. Researchers will monitor side effec…

This early-phase study tests a new treatment using specially engineered natural killer (NK) cells to target and calm overactive B cells in children with autoimmune diseases like lupus and IgA nephropathy. The goal is to see if this therapy is safe and can help control the disease…

This early-phase study tests a new treatment for children with severe systemic sclerosis (scleroderma) that hasn't responded to standard drugs. Doctors will give patients a single infusion of their own immune cells that have been reprogrammed to target and destroy faulty B cells.…

This study tests a new, quickly-made CAR-T cell therapy for people with severe lupus that hasn't responded to standard treatments. The therapy uses a patient's own immune cells, modified to target and attack lupus-causing cells. The main goals are to see if it's safe and if it ca…

This study tests a new treatment using specially engineered immune cells (CAR-NK cells) in children aged 5 and older with severe rheumatic diseases like lupus that have not responded to standard therapies. The cells are designed to target and destroy faulty immune cells that caus…

This early-stage study tests a new treatment using specially engineered immune cells (CAR-NK cells) in 12 children with B cell-related autoimmune diseases like lupus or kidney disease. The goal is to see if it is safe and can control the disease by targeting faulty immune cells. …

This early-stage study tests a new treatment called QT-219C, which uses specially engineered immune cells (CAR-T cells) to target and destroy faulty B cells that cause autoimmune diseases like lupus and kidney disease. The treatment involves a one-time infusion after a short chem…

This study looks at whether a special ultrasound using a contrast dye can help doctors better diagnose abdominal diseases in children. About 108 kids with belly tumors, injuries, or fluid buildup will get this ultrasound. The goal is to see how accurate the test is and to create …

This study looks at how the immune system changes in 6 children with severe lupus who are getting a new treatment called CD3×CD19 BiTE. Researchers will take blood samples over time to track immune cells and see how they relate to disease activity. The goal is to find clues that …

This study follows 1,000 children in China (ages 5-18) who are starting standard allergy shots for dust mite allergies. Researchers will use a detailed blood test to map each child's specific mite allergy profile and track their progress over three years. The goal is to see if ch…

This study looks at why some childhood cancer survivors continue to have symptoms like fatigue, pain, and trouble sleeping. Researchers will ask 600 survivors aged 8-18 about their symptoms and collect stool samples to study gut bacteria. The goal is to find links between gut hea…