Could a common numbing drug shield Babies' lungs after heart surgery?

NCT ID NCT07499154

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether giving the numbing drug lidocaine during heart surgery can reduce lung damage in infants. 320 babies under 1 year old having heart surgery will receive either lidocaine or a placebo. The goal is to see if lidocaine lowers the severity of lung injury after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If it works, this could provide a simple, low-cost way to protect infants' lungs after heart surgery, reducing time on a ventilator and in the ICU.

What could go wrong

This is a Phase 4 trial, but lidocaine is already used for other purposes. The benefit for lung injury is not proven, and there is a risk of side effects like heart rhythm problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONGENITAL HEART DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute lung injury congenital heart disease Lung Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••