Major study to watch kidney swelling in infants – no treatment, just observation

NCT ID NCT07382570

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 330 infants diagnosed with congenital hydronephrosis (kidney swelling) between birth and 6 months of age for three years. Researchers will track whether the condition gets better, stays the same, or worsens using ultrasound scans. The goal is to understand the natural course of the disease so doctors can make better decisions about when to intervene or simply monitor.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to better guidelines for when to treat or wait in infants with congenital hydronephrosis, reducing unnecessary surgeries and preventing kidney damage.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test any therapy. Results may take years and might not change practice if the natural course varies widely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's hospital, Zhejiang Univeristy School of Medicine

    Hangzhou, Zhejiang, 310052, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.