Gene test could make leukemia treatment safer for kids

NCT ID NCT07462299

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to see if using a child's genetic information to decide the dose of a chemotherapy drug (6-MP) can reduce dangerous side effects like low white blood cell counts and infections. About 110 children with acute lymphoblastic leukemia will receive a personalized dose based on their NUDT15 and TPMT genes. The goal is to make maintenance therapy safer while still controlling the disease.

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Conditions

The condition(s) this trial relates to.

childhood acute lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Children's Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

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