Can a shorter steroid course save preemie lungs?
NCT ID NCT07052201
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two different ways of giving the steroid dexamethasone to very premature babies (born before 30 weeks) who have been on a breathing machine for at least two weeks. The goal is to see which treatment better prevents a serious lung condition called bronchopulmonary dysplasia (BPD) or death. About 970 babies will be randomly assigned to either a 10-day lower-dose regimen or a 7-day higher-dose regimen, and researchers will track their breathing progress and long-term development.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chengdu Maternal and Children's Health Care Hospital
Chengdu, China
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Children's Hospital of Chongqing Medical University
Chongqing, China
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Children's Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 0571, China
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First Affiliated Hospital of Kunming Medical University
Kunming, China
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First Affiliated Hospital of Xinjiang Medical University
Xinjiang, China
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Fourth Hospital of Shijiazhuang City
Shijiazhuang, China
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Guangdong Women and Children Hospital
Guangdong, China
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Guangxi Maternal and Child Health Hospital
Guangxi, China
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Guiyang Maternity and Child Health Care Hospital
Guiyang, China
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Guizhou Provincial People's Hospital
Guizhou, China
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Jiangxi Maternal and Child Health Hospital
Nanchang, China
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Nanjing Maternity and Child Health Care Hospital
Nanjing, China
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Ningbo Women & Children's Hospital
Ningbo, China
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QuanZhou Women and Children's Hospital
Quanzhou, China
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Qujing Maternal and Child Health Hospital
Qujing, China
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Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
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Shengjing Hospital
Shengyang, China
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Shenzhen Maternal and Child Health Hospital
Shenzhen, China
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The First Hospital of Jilin University
Jilin City, China
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Women and Children's Hospital of Chongqing Medical University
Chongqing, China
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Xiamen Women's and Children's Hospital
Xiamen, China
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Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
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Zhangzhou Affiliated Hospital of Fujian Medical University
Zhangzhou, China
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Zhengzhou Children's Hospital, China
Zhengzhou, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Gentle touch and voice may ease stress for premature babies — a pilot trial puts it to the test
- Can a steroid shot into the windpipe protect preemies' lungs?
- Gentler resuscitation may protect fragile lungs in tiniest babies
- Nasal fentanyl spray could ease painful eye exams for premature babies
- Could cameras and microphones replace wires for premature babies?