Can a steroid shot into the windpipe protect preemies' lungs?
NCT ID NCT07725575
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial tests whether giving the steroid budesonide directly into the windpipe, together with surfactant, can prevent bronchopulmonary dysplasia — a chronic lung disease — in very preterm infants (born before 32 weeks or weighing under 1500 grams) who have respiratory distress syndrome. About 86 newborns will receive either budesonide plus surfactant or surfactant alone. Researchers will track lung health until 36 weeks after the mother's last menstrual period to see if the steroid lowers the chance of lung damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- budesonide (a corticosteroid) given into the windpipe along with surfactant
- What this could lead to
- If it works, this could offer a simple way to reduce chronic lung disease in the tiniest newborns.
- What could go wrong
- This is a single-center trial with 86 infants, so results may not apply everywhere. Corticosteroids in newborns carry risks, including possible effects on growth and development.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Cipto Mangunkusumo Hospital
Jakarta, DKI Jakarta, 10430, Indonesia
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