Shanghai Zhongshan Hospital
Clinical trials sponsored by Shanghai Zhongshan Hospital, explained in plain language.
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Drug cocktail tested to extend lives in liver cancer
Disease control CompletedThis study looked back at medical records to see if adding three oral medications (thalidomide, carmofur, and compound mylabris capsules) to a standard liver cancer procedure (TACE) helped patients live longer. It involved 545 people with advanced liver cancer that couldn't be re…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Can a cholesterol drug prevent future heart attacks?
Disease control CompletedThis study looked at whether the drug evolocumab could reduce the risk of future major heart problems in people who had a heart attack and had multiple blocked arteries. Researchers followed 1,862 patients for two years to see if the drug lowered risks like another heart attack, …
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Study compares survival rates for two esophageal cancer surgeries
Disease control CompletedThis study looked back at the medical records of over 1,600 patients with esophageal cancer to compare two different surgical techniques. Researchers wanted to see if a newer, less invasive method (IVMTE) led to fewer complications after surgery and better long-term survival comp…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Diabetes drug tested to protect the heart from scarring
Disease control CompletedThis study investigated whether the diabetes medication canagliflozin could reduce harmful scarring in the heart muscle of people with type 2 diabetes who are at high risk for heart disease. Researchers used special heart scans to measure scarring in 45 participants before and af…
Phase: PHASE4 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope to save legs from amputation: study tests advanced techniques for severe artery blockages
Disease control CompletedThis study observed 322 patients with severe, complete blockages inside previously placed leg artery stents. It aimed to see how well newer, minimally invasive procedures could keep these arteries open and prevent patients from needing repeat surgeries over two years. The researc…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New 3D method could help doctors better track cancer treatment effectiveness
Diagnosis CompletedThis study looked at whether a new 3D measurement method (TDTP-RECIST) works better than the current standard (RECIST 1.1) for tracking how irregularly shaped tumors respond to pre-surgery treatment. Researchers reviewed past medical scans and records of 120 adults with breast, p…
Sponsor: Shanghai Zhongshan Hospital • Aim: Diagnosis
Last updated Mar 30, 2026 14:32 UTC
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Could a simple scan replace invasive heart tests?
Diagnosis CompletedThis study tested if starting with a special CT scan could help doctors diagnose a type of heart attack without needing an invasive angiogram for all patients. It involved 180 people with suspected heart attacks and compared the CT-first approach to the standard practice of immed…
Phase: NA • Sponsor: Shanghai Zhongshan Hospital • Aim: Diagnosis
Last updated Mar 27, 2026 12:40 UTC
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AI scans lungs to predict survival in critical patients
Diagnosis CompletedThis study tested whether an artificial intelligence (AI) tool could help doctors better manage Acute Respiratory Distress Syndrome (ARDS), a severe form of lung failure. The AI analyzed patients' chest CT scans and medical data to classify the disease's severity, predict the ris…
Sponsor: Shanghai Zhongshan Hospital • Aim: Diagnosis
Last updated Mar 23, 2026 15:17 UTC
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New sedation drug tested to make critical ICU procedure safer
Symptom relief CompletedThis study compared two drugs, ciprofol and propofol, used to sedate patients before inserting a breathing tube in the intensive care unit (ICU). It involved 100 critically ill adults to see which drug caused fewer dangerous drops in blood pressure and other complications during …
Phase: PHASE4 • Sponsor: Shanghai Zhongshan Hospital • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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Scientists develop model to personalize lung cancer treatment
Knowledge-focused CompletedThis study looked at 3000 people with advanced lung cancer to create a prediction model. Researchers analyzed medical scans, blood tests, and lung function results to predict which patients would benefit most from immunotherapy combined with chemotherapy. The model also aims to i…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists probe hidden link between stress, blood sugar, and the heart in ICU
Knowledge-focused CompletedThis study aimed to understand the connection between high blood sugar caused by severe illness and changes in heart rate patterns, which reflect nervous system stress. Researchers observed 20 non-diabetic, critically ill adults to see if blood sugar and hormone levels were linke…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC