Shanghai Zhongshan Hospital
Clinical trials sponsored by Shanghai Zhongshan Hospital, explained in plain language.
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Triple-Drug cocktail boosts survival in unresectable liver cancer
Disease control CompletedThis study tested whether adding a three-drug cocktail (thalidomide, carmofur, and compound mylabris capsules) to the standard procedure called TACE could help people with liver cancer that cannot be removed by surgery. Researchers looked at 545 patients and measured how long the…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 17, 2026 02:04 UTC
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Diabetes drug may protect hearts by reducing scarring
Disease control CompletedThis study looked at whether canagliflozin, a diabetes medicine, can reduce scarring in the heart muscle of people with type 2 diabetes who are at high risk for heart problems. 45 participants took the drug, and researchers used MRI scans to measure changes in heart scarring. The…
Phase: PHASE4 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Heart attack survivors: new hope from Cholesterol-Lowering drug?
Disease control CompletedThis study looked at whether evolocumab, a cholesterol-lowering drug, can reduce the risk of major heart problems in people who had a heart attack and have blockages in multiple heart arteries. Researchers analyzed data from 1,862 patients to see if the drug lowers the chance of …
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New real-world study explores best ways to reopen blocked leg stents
Disease control CompletedThis study followed 322 people with completely blocked stents in their leg arteries (a condition called Tosaka III in-stent restenosis) to see how well different endovascular treatments worked. The main goal was to measure how many patients avoided needing another procedure withi…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New CT approach could spare many heart patients from unnecessary surgery
Diagnosis CompletedThis study tested whether starting with a special CT scan (CT perfusion) instead of going straight to heart catheterization can safely reduce the need for invasive procedures in patients with a mild heart attack (NSTEMI). Researchers enrolled 180 adults with chest pain and elevat…
Phase: NA • Sponsor: Shanghai Zhongshan Hospital • Aim: Diagnosis
Last updated May 13, 2026 16:00 UTC
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New sedative may reduce dangerous blood pressure drops during emergency intubation
Symptom relief CompletedThis study tested whether a newer sedative called ciprofol causes fewer dangerous drops in blood pressure than the standard drug propofol when placing a breathing tube in critically ill ICU patients. About 100 adults aged 18 to 85 who needed emergency intubation took part. The go…
Phase: PHASE4 • Sponsor: Shanghai Zhongshan Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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AI reads lung scans to predict ARDS outcomes
Knowledge-focused CompletedThis study looked at whether artificial intelligence (AI) could help doctors better diagnose and predict the course of acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers used chest CT scans from 400 intensive care unit patients to train an AI model …
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 02:06 UTC
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New model aims to predict lung cancer treatment success and dangerous side effect
Knowledge-focused CompletedThis study looked at 3,000 people with advanced non-small cell lung cancer to see if a model using CT scans, lung function tests, and blood markers could predict how well immunotherapy combined with chemotherapy works. It also aimed to predict the risk of a serious side effect ca…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 02:04 UTC
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New 3D method may improve tumor measurement for irregular cancers
Knowledge-focused CompletedThis study looks at better ways to measure how irregularly shaped tumors respond to treatment before surgery. Researchers compared a new 3D method (TDTP-RECIST) with the standard approach (RECIST 1.1) using past scans from 120 adults with breast, pancreatic, or biliary cancers. T…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 02:02 UTC
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ICU blood sugar mystery: heart rate clues revealed
Knowledge-focused CompletedThis study looked at 20 non-diabetic critically ill patients to see if there is a link between blood sugar levels and heart rate variability (HRV), a measure of nervous system health. Researchers focused on stress-induced high blood sugar, common in ICUs, and its connection to ne…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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AI reads your Heart's electrical signals to predict failure years in advance
Knowledge-focused CompletedThis study used artificial intelligence to analyze electrocardiograms (ECGs) from nearly 287,000 adults in China and the United States. The goal was to see if the AI could predict who might develop a type of heart failure (with reduced pumping ability) up to five years before sym…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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AI spots hidden heart valve risks in routine scans
Knowledge-focused CompletedThis study looked at whether artificial intelligence (AI) can predict if a person's heart valve disease will get worse. Researchers used data from over 116,000 adults who had routine electrocardiograms (ECGs) and chest X-rays. The goal was to see if combining these tests with AI …
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC
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Which surgery is better for esophageal cancer? new study compares outcomes
Knowledge-focused CompletedThis study looked at 1661 people with esophageal cancer to compare two types of surgery: a newer, less invasive method (IVMTE) and a standard one (VME). Researchers wanted to see which approach led to better recovery and longer survival. The goal was to gather information to help…
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 07, 2026 18:38 UTC