Heart attack survivors: new drug may cut risk of another cardiac event

NCT ID NCT06740552

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether evolocumab, a cholesterol-lowering injection, can reduce major heart problems in people who had a heart attack and have several blocked arteries. Researchers analyzed data from 1862 patients to see if the drug lowers the risk of cardiac death, another heart attack, or heart failure hospitalization. The study used existing medical records rather than a traditional trial, so results are suggestive but not definitive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

evolocumab (a cholesterol-lowering injection given every two weeks)

What this could lead to

If it works, this could show that evolocumab reduces the chance of another heart attack or heart failure in people with multiple blocked arteries after a first heart attack.

What could go wrong

This is a completed observational analysis, not a controlled experiment, so results may be less reliable. The benefit may be small or not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zhongshan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 200000, China