New sedative ciprofol may be safer for emergency intubation in ICU

NCT ID NCT06344949

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether ciprofol, a newer sedative, causes fewer drops in blood pressure than the standard drug propofol when ICU patients need an emergency breathing tube. About 100 critically ill adults will receive one of the two drugs before intubation. The goal is to find a safer sedation method for these high-risk procedures.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Ciprofol
What this could lead to
If ciprofol proves safer, it could offer a more stable sedation option for emergency intubations in the ICU, reducing complications like low blood pressure.
What could go wrong
This is a small pilot study with only 100 patients, so results may not apply broadly. The drug is new and its advantages over propofol are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zhongshan Hospital Affiliated to Fudan University

    Shanghai, Shanghai Municipality, 200032, China