Qilu Pharmaceutical Co., Ltd.

This study tests a new drug (QLS31905) combined with chemotherapy, with or without another drug (QL2107), in people with advanced bile duct cancer that has a specific marker (CLDN18.2). The goal is to see if the combination shrinks tumors. About 120 adults who have not had prior …

This study tests if a new drug called QL2302 works as well as the approved drug Tezspire for adults with severe asthma that is not controlled by current treatments. About 636 people will get injections every 4 weeks for 48 weeks, then be monitored for 12 more weeks. The main goal…

This study tests a new tablet called QLS1410 for people with primary aldosteronism, a condition where the body makes too much of a hormone that raises blood pressure. About 60 adults will receive either the study drug or a placebo daily for up to 12 weeks. The main goal is to see…

This early-stage trial tests a new drug called QLS2313 in 124 adults with blood cancers (like lymphoma or leukemia) that have returned or stopped responding to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors…

This study tests a new drug called QLS12010 for adults with moderate-to-severe rheumatoid arthritis, a condition causing joint pain and swelling. About 180 participants will receive either the drug or a placebo to see if it reduces disease activity safely. The main goal is to mea…

This study tests a new medicine called QLC7401 in adults with high cholesterol or mixed dyslipidemia who are not on other cholesterol drugs. About 510 participants will get either the study drug or a placebo as a shot under the skin. The main goal is to see how much it lowers "ba…

This study tests a new injectable drug called QLC7401 for people with high cholesterol that remains high even with standard treatments. About 780 adults will receive either the drug or a placebo to see if it safely lowers their LDL (bad) cholesterol. The goal is to provide an add…

This study tests a new tablet (QLC1401) combined with standard targeted therapies for people with a common type of advanced breast cancer (ER+/HER2-). About 96 participants will join to find the safest dose and see if the combination shrinks tumors. The goal is to better control …

This early-stage trial tests the safety and tolerability of a new drug called QLS1410 in 78 healthy Chinese adults and people with mild high blood pressure. Researchers will give single and multiple doses to see how the body processes the drug and how food affects it. The goal is…

This study tests a new medicine called QLS1410 for people whose high blood pressure is not controlled by current treatments. About 260 adults will receive either the study drug or a placebo for 12 weeks. The main goal is to see if QLS1410 can safely lower blood pressure more than…

This study tests whether a new drug called QL2106 works as well as the approved drug Tremfya for people with moderate to severe plaque psoriasis. About 318 adults will receive either QL2106 or Tremfya by injection, and doctors will check how much their skin clears up after 16 wee…

This study tests a new medicine called QL0911 in children aged 1 to 17 with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing easy bruising and bleeding. The goal is to see if QL0911 can safely raise platelet counts to safer le…

This study tests whether a new drug called QL2107 works as well as the standard immunotherapy Keytruda (pembrolizumab) for people with non-small cell lung cancer that has been surgically removed. About 122 adults with stage II or IIIA lung cancer will receive either QL2107 or Key…

This early-stage study tests a new drug called QLS5316 in about 300 people with advanced solid tumors (such as colorectal, stomach, head and neck, or lung cancer) that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, a…

This study tests a new drug combination (QLC5513 plus QL1706, with or without platinum chemotherapy) in people with advanced or metastatic solid tumors that have not responded to standard treatments. The goal is to find the safest dose and see if the combination can shrink tumors…

This study tests a new drug called QLG1218 (daprodustat) for anemia in people on kidney dialysis. About 100 Chinese adults aged 18-75 who are on dialysis and have low red blood cells will take either the new pill or a standard injected drug. The goal is to see if the pill works a…

This study tests a new eye injection called QL1207H against an approved drug (Eylea) for people with wet age-related macular degeneration, a leading cause of vision loss. About 356 adults aged 50 and older with active disease will receive injections every 4 weeks for 3 doses, the…

This study tests two experimental drugs, QLC5508 and QLH12016, alone or with standard hormone therapies (abiraterone or enzalutamide) in 212 men with advanced prostate cancer that has spread. The goal is to find safe doses and see if the combinations shrink tumors or lower PSA le…

This study tests a new drug called QLS4131, given as a shot under the skin, combined with other medicines for people with malignant plasma cell neoplasms, a group of blood cancers including multiple myeloma. The goal is to see if these combinations are safe and help shrink or con…

This study tests a new drug called QLS5132, given with other cancer treatments, for people with advanced solid tumors like stomach, lung, ovarian, or endometrial cancer. The goal is to find safe doses and see if the combination shrinks tumors. About 626 participants will receive …

This study tests whether adding romiplostim N01 to standard treatment helps people with severe aplastic anemia recover healthy blood cell levels faster. About 210 participants will receive either the drug or a placebo alongside standard therapy. The main goal is to see if more pa…

This early-phase study tests a new drug called QLS5308 in about 192 people with advanced solid tumors that have spread and cannot be removed by surgery or radiation. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. This is a firs…

This study compares a new medicine called QLG1091 to an existing drug, Rybelsus, in people with type 2 diabetes who already take metformin. About 478 adults will receive either QLG1091 or Rybelsus for 26 weeks to see if the new drug works just as well at lowering blood sugar. The…

This study tests a new medicine called QLC7401 for people with a genetic condition that causes very high cholesterol (heterozygous familial hypercholesterolemia). About 120 adults who are already on cholesterol-lowering drugs will receive either QLC7401 or a placebo as a shot. Th…

This is the first study in humans testing a new cancer drug called QLS5212. It aims to find a safe dose and schedule for adults with advanced solid tumors that cannot be surgically removed. The study will check how the body handles the drug and look for early signs that it might …

This study tests a new drug called QLS12010 in 102 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition that causes abscesses and nodules. The trial has two parts: first, an open-label phase to see if the drug works and is safe; second, a placebo…

This study tests an experimental capsule called QLS12010 in 160 adults with moderate-to-severe atopic dermatitis (eczema). Participants will receive either the drug or a placebo for 16 weeks. The main goal is to see if the drug reduces eczema severity and itching better than a pl…

This early-stage study tests a new drug called QLH2405 in healthy volunteers and people with mild Alzheimer's or mild cognitive impairment. The main goal is to check if the drug is safe and how the body processes it. About 68 participants will receive a single injection and be mo…

This early-stage study tests a new drug called QL2302 in 178 healthy adults aged 18-45. It compares how the body processes QL2302 versus the approved drug Tezspire, and checks for side effects. The goal is to see if QL2302 works similarly, not to treat any disease.

This early-stage study tests the safety and effects of an experimental drug, QLS7305, in 60 healthy adults in China. Participants receive either the drug or a placebo, and are monitored closely for up to 337 days. The study also looks at how the drug affects the immune system and…

This early-stage study looks at how taking a new drug (QLS1410) with or without food changes its levels in the blood. It involves 12 healthy Chinese adults and is not intended to treat any condition. The results will help guide future dosing instructions for people with uncontrol…

This early-stage study tests the safety of a new drug called QL2401 in 70 healthy Chinese adults. Participants receive either the drug or a placebo to check for side effects and how the drug moves through the body. The goal is to gather essential safety data before testing the dr…

This early-stage study tests a new drug called QL2109 in 102 healthy Chinese men to see if it behaves like the approved drug Darzalex. The goal is to compare how the body processes each drug and check for side effects. This is a first step before testing in patients with multiple…