New pill could ease painful skin condition for those failed by antibiotics

NCT ID NCT07417917

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase II trial tests QLS12010, an oral capsule, in 102 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition. The study has two parts: an open-label proof-of-concept phase and a placebo-controlled dose-ranging phase. Participants must have tried and failed or been unable to take antibiotics for HS. The goal is to see if the drug reduces abscesses and inflammatory nodules safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
QLS12010 capsules
What this could lead to
If successful, this could lead to a new oral treatment option for people with moderate-to-severe hidradenitis suppurativa who haven't responded to antibiotics.
What could go wrong
This is an early Phase II trial with only 102 participants, so results may not apply to everyone. The drug's safety and effectiveness are still unproven, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADULTS WITH MODERATE-TO-SEVERE HIDRADENITIS SUPPURATIVA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••