New shot could tame high cholesterol without daily pills

NCT ID NCT07444086

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests a new injectable drug called QLC7401 in 510 adults with high cholesterol or mixed dyslipidemia who are not on other cholesterol treatments. Participants receive either the drug or a placebo as a shot under the skin. The main goal is to see how much it lowers 'bad' LDL cholesterol over time. Researchers will also check safety and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
QLC7401 injection
What this could lead to
If successful, this could provide a new injectable treatment option to help control high cholesterol and reduce heart disease risk.
What could go wrong
This is an early-stage Phase 3 trial, so results are not yet known. The drug may not lower cholesterol enough or could cause side effects. It is only tested in people not on other cholesterol meds.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY HYPERCHOLESTEROLEMIA OR MIXED HYPERLIPIDEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.