Nationwide Children's Hospital

This study tested an intensive two-step chemotherapy approach for children and young adults with recurrent brain germ cell tumors. First, patients received several rounds of three chemotherapy drugs, then they received very high-dose chemotherapy supported by their own previously…

This study tested a new approach to rehab for a common back stress fracture in teen athletes. It compared starting physical therapy right after diagnosis to the standard method of waiting until the pain was gone. The goal was to see if the immediate start was safe and could help …

This study tested whether a medicine called baclofen could help children with rumination syndrome, a condition that causes repetitive, effortless regurgitation of food. Fifty children aged 4-18 took either baclofen or a placebo (a dummy pill) for four weeks while continuing their…

This study tested whether providing fentanyl test strips and education in Ohio drug courts is a practical way to help prevent overdoses. It involved 653 adults enrolled in various Ohio drug courts who reported using illicit stimulants. The goal was to see if this 'harm reduction'…

This study tested whether a therapy called gastric electrical stimulation (GES) could help children with severe, long-lasting nausea and vomiting that hasn't improved with standard medicines. For eight days, 30 children had a thin tube placed to deliver gentle electrical pulses t…

This study tested if a gentle electrical stimulation to a nerve near the ankle could help children with severe constipation caused by uncoordinated pelvic floor muscles. Researchers compared the real stimulation to a fake (sham) treatment in 40 children aged 8-18. The goal was to…

This study tested how easy and helpful a Spanish-language mobile app is for parents caring for a child who recently had a bone marrow transplant. Researchers worked with 30 Spanish-speaking parents to see if the app was user-friendly and acceptable for managing care after their c…