Could a muscle relaxant stop kids from vomiting after meals?

NCT ID NCT05975684

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether the drug baclofen can reduce vomiting in children with rumination syndrome, a condition where food comes back up soon after eating. Fifty children aged 4 to 18 took either baclofen or a placebo for 4 weeks. Researchers measured how many kids vomited once a week or less using symptom surveys.

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Conditions

The condition(s) this trial relates to.

rumination disorder Rumination Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nationwide Children's Hospital

    Columbus, Ohio, 73205, United States