New chemo combo shows promise for rare childhood brain tumors

NCT ID NCT01270724

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tested a new combination of chemotherapy drugs (GemPOx) followed by a single round of high-dose chemo and stem cell rescue in 10 children whose brain germ cell tumors had come back or continued to grow. The goal was to see how many patients responded to the treatment and could move forward with the stem cell procedure. While the approach aims to control the disease, ongoing monitoring and potential future treatments may still be needed.

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Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • The Ohio State University Wexner Medical Center_The James Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.