Nationwide Children's Hospital

This study aims to find out which of two standard chemotherapy treatments is better at preserving long-term thinking skills and quality of life in young children with a specific type of low-risk brain cancer. It will enroll 96 children under 5 years old who have not yet started t…

This study is testing a new treatment for acute myeloid leukemia (AML) that has returned or not responded to other therapies. It uses specially engineered immune cells from a healthy donor, designed to find and attack the cancer. The first part finds the safest dose, and the seco…

This study is testing a new program called PIONEER, which teaches parents special techniques to help their hospitalized infants learn to eat by mouth. The goal is to see if this program is better than standard care at helping babies avoid needing a permanent feeding tube (g-tube)…

This study is testing whether a drug called tovorafenib can help children and young adults live longer after being diagnosed with aggressive brain tumors, including a type called DIPG. The drug is given after standard radiation treatment and targets tumors with specific genetic c…

This study aims to understand how virtual reality (VR) helps reduce pain in children with burns. Researchers will use a special, safe cap to scan brain activity in 4 children aged 6-17 during their burn dressing changes, both with and without VR. The goal is to find brain signals…

This study aims to use a special monitor to more accurately measure how quickly a common muscle relaxant (rocuronium) takes effect and wears off during surgery. It will involve 130 patients who need this medication for their operation. The goal is to gather better data to help do…