Can a drug reverse immune shutdown in kids with sepsis?
NCT ID NCT05266001
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called GM-CSF in 141 children with sepsis who had multiple organ failure and a weakened immune system. The goal was to see if the drug could help their organs recover better than a placebo. The trial is complete, and results will show if this approach improves survival and quality of life.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Benioff Children's Hospital - Mission Bay
San Francisco, California, 94143, United States
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Benioff Children's Hospital - Oakland
Oakland, California, 64609, United States
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CS Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Michigan
Detroit, Michigan, 48202, United States
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Children's Hospital of Minnesota
Minneapolis, Minnesota, 55404, United States
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Children's Hospital of Orange County
Orange, California, 92868, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
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Children's Hospital of San Antonio
San Antonio, Texas, 78207, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Duke University
Durham, North Carolina, 27705, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53233, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Mercy Children's Hospital
Kansas City, Missouri, 64108, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Pennsylvania State University
Hershey, Pennsylvania, 17033, United States
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Primary Children's Hospital
Salt Lake City, Utah, 84158, United States
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Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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University of California - Davis
Sacramento, California, 95618, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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Virginia Commonwealth University
Richmond, Virginia, 23298, United States