Could a 'Stomach Pacemaker' stop Kids' chronic nausea?

NCT ID NCT07474415

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a device that sends small electrical pulses to the stomach can help children with severe, long-lasting nausea and vomiting. Thirty kids who hadn't gotten better with standard treatments took part. Each child had a temporary pacing lead placed through a tube into the stomach, and the device was turned off for four days and on for four days without them knowing which phase they were in. Researchers measured symptoms and how much the kids could eat or drink to see if the stimulation made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gastric electrical stimulation device
What this could lead to
If it works, this could offer a new treatment option for children with severe nausea and vomiting that hasn't responded to standard care.
What could go wrong
This is a small, early-stage study with only 30 participants. The results may not apply to all children, and the temporary nature of the stimulation means long-term effects are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

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