Massachusetts Eye And Ear Infirmary

This study is testing if a high dose of a common cholesterol-lowering drug (atorvastatin) can slow the progression of intermediate age-related macular degeneration (AMD), a leading cause of vision loss. Researchers will give the drug to 21 participants and use a special 'dark ada…

This study is testing whether N-acetyl cysteine (NAC) eye drops can slow the progression of Fuchs' endothelial corneal dystrophy, a common eye disease that currently requires corneal transplant surgery. About 45 adults with advanced Fuchs' and cataracts will use either NAC drops …

This study is testing if a daily eye drop called netarsudil can prevent a serious complication called proliferative vitreoretinopathy (PVR), which is scarring that can cause the retina to detach again after surgery. Researchers will give the drops to 48 patients before and after …

This study aims to improve hearing for people with cochlear implants by testing personalized programming methods. Researchers will work with 200 children and adults who have cochlear implants to understand how different programming approaches affect hearing development and speech…

This study is testing whether treating donor cornea tissue with a special light and solution before transplant makes it safer and more effective for patients at high risk of transplant failure. Researchers will compare treated and untreated donor corneas in 96 adults who need a h…

This early-stage study is testing a new way to deliver medicine for a recurring eye condition called cystoid macular edema, which causes swelling in the center of the retina. Researchers are evaluating a special contact lens designed to slowly release a steroid drug (dexamethason…

This study is testing a computer program called DystoniaNet that uses artificial intelligence to help doctors diagnose isolated dystonia, a movement disorder. The goal is to see if this tool can make diagnosis faster and more accurate, as current methods often lead to misdiagnosi…

This study is testing if a small, wearable device that delivers a gentle, undetectable electrical stimulation can help improve balance and make walking easier for older adults who have trouble with stability. Researchers want to see if using the device can increase walking speed …

This study is testing different designs of special prism glasses to help people with visual field loss see more to the side, which can help them spot obstacles while walking. Researchers will fit and test these glasses on about 20 participants over several visits. The goal is to …

This study aims to understand what causes different types of focal dystonia, a condition that causes involuntary muscle spasms in specific body parts like the eyes, jaw, hands, or voice. Researchers will use brain scans to compare the brain structure and activity of people with d…

This study is testing a blood test to see if it can find leftover cancer cells after surgery or track how well immunotherapy is working for people with a type of skin cancer called cutaneous squamous cell carcinoma. Researchers will collect blood samples from 60 participants over…

This study aims to understand how the brain functions differently in people with two neurological voice disorders: laryngeal dystonia (spasmodic dysphonia) and voice tremor. Researchers will use brain scans and other measurements to compare brain activity in 165 participants with…

This study aims to find clearer ways to tell the difference between two similar-sounding neurological voice disorders: laryngeal dystonia (which causes strained or interrupted speech) and voice tremor (which causes a shaky voice). Researchers will use voice recordings, imaging, a…

This study aims to understand how voice problems occur in people with dystonia or essential tremor who are already scheduled for deep brain stimulation (DBS) surgery. Researchers will measure brain activity while participants speak during surgery to see how DBS affects voice cont…