Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
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Eye injection shows promise in preventing repeat retinal detachment
Disease control Not yet recruitingThis early-stage study tests whether an injection of the drug topotecan into the eye can safely prevent retinal detachment from coming back in people with a condition called proliferative vitreoretinopathy (PVR). About 50 adults having retinal detachment surgery will either recei…
Phase: PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Could a probiotic help save sight in diabetes?
Disease control Not yet recruitingThis pilot study tests whether a daily probiotic supplement (Lactobacillus plantarum 299v) can reduce retinal swelling and improve vision in people with diabetic macular edema. Thirty-six participants will take the probiotic twice daily for four months. Researchers will measure c…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Eye surgery breakthrough? tiny trial tests humira injection during corneal implant
Disease control Not yet recruitingThis early-stage trial will test whether injecting adalimumab (Humira) into the eye during Boston KPro surgery is safe for 8 patients with severe corneal damage. The study focuses on side effects and tolerability, not yet on how well it works. It is for people who have run out of…
Phase: PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Tailoring cochlear implants to inner ear nerve health may boost speech understanding in noisy places
Symptom relief Not yet recruitingThis study tests whether adjusting cochlear implant programming based on the health of the hearing nerve in different parts of the inner ear can help people understand speech better in noisy settings. Researchers will compare two experimental sound-processing strategies against e…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC