Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
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New eye drug combo aims to improve rare corneal transplant outcomes
Disease control Not yet recruitingThis early-stage study tests whether an injection of adalimumab (Humira) given during Boston Keratoprosthesis (KPro) eye surgery is safe. It involves 8 adults with severe corneal damage who have few other options. The main goal is to check for side effects, not to cure the condit…
Phase: PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 17, 2026 05:34 UTC
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Eye injection could stop retinal detachment from coming back
Disease control Not yet recruitingThis early-stage study tests whether an injection of the drug topotecan into the eye can safely prevent retinal detachment from recurring in people with a condition called proliferative vitreoretinopathy (PVR). About 50 adults having surgery for retinal detachment will either rec…
Phase: PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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Could a probiotic help save sight in diabetes?
Disease control Not yet recruitingThis study tests whether taking a probiotic (Lactobacillus plantarum 299v) twice daily for four months can reduce retinal swelling and improve vision in people with diabetic macular edema. Thirty-six adults with the condition will take the supplement, and their results will be co…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 14, 2026 12:05 UTC