Massachusetts Eye And Ear Infirmary

This phase II trial tests whether aspirin can delay tumor growth and maintain hearing in people with vestibular schwannoma (acoustic neuroma), a non-cancerous brain tumor. About 97 participants are randomly assigned to take aspirin or a placebo twice daily. The study tracks how l…

This study tests whether injecting doxycycline directly into skin schwannomas can shrink them in people with neurofibromatosis type 2 (NF2). Nineteen participants will receive up to three injections per tumor, with the dose based on tumor size. The goal is to find a less invasive…

This study tests a new training method for people who have lost part of their vision (homonymous hemianopia or quadrantanopia) to help them scan more effectively while driving. Sixteen participants will use reminder cues to practice making larger head scans toward their blind sid…

This study tests two types of high-power prism glasses designed to expand the field of view for people with homonymous hemianopia, a condition where the same half of vision is missing in both eyes. About 64 participants will use the glasses while walking in a virtual reality simu…

This study aimed to test a closed-loop sound therapy for people with chronic tinnitus (ringing in the ears) or hyperacusis (sensitivity to sound). The therapy was designed to retrain the brain's response to sounds. However, the trial was withdrawn before any participants were enr…

This study tests a virtual reality headset that uses special prisms to expand the field of view for people with tunnel vision or hemianopia (blindness in half the visual field). Fifteen participants will walk in a real environment while wearing the headset and respond to virtual …

This study aimed to compare how corneas with Fuchs endothelial corneal dystrophy (FECD) and healthy corneas swell and recover after wearing a contact lens for three hours. Researchers planned to measure corneal thickness before and after the lens was removed, tracking swelling an…

This study planned to test whether playing specially designed video games at home could improve the ability of older adults with high-frequency hearing loss to understand speech in noisy environments. Participants would have played either an immersive audiomotor game or an audito…