Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
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Drug trial aims to tame tough thyroid tumors before surgeons operate
Disease control OngoingThis study is testing if taking the drug lenvatinib before surgery can help control advanced thyroid cancer that has grown into nearby structures. The goal is to shrink the tumors, making them easier and safer to remove completely. About 30 adults with this specific type of invas…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Needle instead of knife? simple injection could shrink painful NF2 tumors
Disease control OngoingThis study is testing whether injecting an antibiotic called doxycycline directly into skin tumors can shrink them in people with Neurofibromatosis Type 2 (NF2). The goal is to find a simpler, less risky alternative to surgical removal. Researchers are measuring tumor size change…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Common aspirin tested to halt growth of rare ear tumors
Disease control OngoingThis study is testing whether taking aspirin daily can slow or stop the growth of vestibular schwannomas, which are non-cancerous tumors affecting hearing and balance nerves. About 97 patients aged 12 and older will be randomly assigned to take either aspirin or a placebo pill fo…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Feb 24, 2026 14:07 UTC
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Could a simple blood test spot anal cancer early?
Diagnosis OngoingThis study is testing whether a new blood test can help screen for anal precancer and cancer. Researchers are enrolling about 100 people who have had anal HPV screening and some from the general population. The goal is to see if this less invasive test can accurately identify who…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Apr 01, 2026 14:43 UTC
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Eye stress test could predict vision loss risk
Diagnosis TerminatedThis study aimed to develop a new way to measure how well the inner layer of the cornea works in people with Fuchs' dystrophy, a common cause of vision loss. Researchers planned to have healthy volunteers and patients with the disease wear a special contact lens as a 'stress test…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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New prism aims to widen the world for those with one eye
Symptom relief OngoingThis study is testing a special prism device designed to help people who are blind in one eye. The goal is to see if wearing the prism can help them spot pedestrians more quickly and accurately during a simulated walking task. The research involves a small, early-stage test to se…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Apr 02, 2026 00:41 UTC
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Video game aims to train ears for noisy world
Symptom relief TerminatedThis study aimed to see if playing a special video game could help older adults with high-frequency hearing loss understand speech better in noisy environments, like restaurants. Researchers planned to compare the game's effects to a memory training game and track changes in brai…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Could a new sound therapy quiet the ringing in your ears?
Symptom relief TerminatedThis study aimed to test a new, non-invasive sound therapy for people with chronic tinnitus (ringing in the ears) and hyperacusis (sensitivity to sound). The therapy was designed to use special sounds to help retrain the brain's hearing system. The goal was to reduce the distress…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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New glasses aim to help people see dangers They've been missing
Symptom relief OngoingThis study is testing two different designs of special prism glasses to see which one better helps people with half-field vision loss. Participants will try each type of glasses at home for four weeks to see if they improve their ability to spot approaching people or obstacles on…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Mar 16, 2026 15:27 UTC
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Virtual reality glasses could help prevent collisions for the visually impaired
Knowledge-focused OngoingThis study is testing whether special glasses that expand what people can see might help those with partial blindness walk more safely. Researchers are using virtual reality to create a test where participants walk while spotting virtual pedestrians. The goal is to measure if the…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC