Massachusetts Eye And Ear Infirmary

This study tests whether injecting doxycycline directly into skin tumors (schwannomas) can shrink them in people with neurofibromatosis type 2 (NF2). About 19 participants will receive the injections, and doctors will measure tumor size changes over time. The goal is to find a le…

This study tests whether giving the drug lenvatinib before surgery can help doctors more completely remove advanced thyroid cancer that has spread outside the gland. About 30 adults with this type of cancer will receive lenvatinib for a short time before their operation. The main…

This study tests whether taking aspirin can slow the growth of vestibular schwannomas (non-cancerous brain tumors) and help preserve hearing. About 97 people aged 12 and older with these tumors are randomly assigned to receive either aspirin or a placebo. The main goal is to see …

This study tests a new training method for people who have lost part of their vision (homonymous hemianopia or quadrantanopia) to help them scan more effectively while driving. Sixteen participants will use reminder cues to practice making early, large head scans toward their bli…

This study tests two types of high-power prism glasses designed to expand the field of view for people with homonymous hemianopia, a condition where the same half of vision is missing in both eyes. Sixty-four participants will wear the glasses while walking in a virtual reality t…

This study tests a virtual reality headset that uses special prisms to expand the field of view for people with vision loss, such as tunnel vision or hemianopia. About 15 participants will walk in a real environment while the headset shows virtual pedestrians, and researchers wil…

This study aimed to compare how the cornea swells and recovers after wearing a contact lens in people with Fuchs' endothelial corneal dystrophy versus healthy volunteers. Researchers planned to measure corneal thickness changes and recovery time. The study was withdrawn before en…

This study was withdrawn before enrolling any participants. It aimed to understand why older adults with high-frequency hearing loss struggle to hear speech in noisy places. Researchers planned to use a listening game to see if it could improve speech understanding, while trackin…

This study was designed to test a new sound therapy for people with tinnitus (ringing in the ears) and hyperacusis (sensitivity to sound). The goal was to see if the therapy could reduce symptoms and improve hearing in noise. However, the study was withdrawn before any participan…