Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
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Could a Pre-Surgery drug improve thyroid cancer outcomes?
Disease control CompletedThis study tested whether giving the drug lenvatinib before surgery helps remove advanced thyroid cancer more completely. 29 adults with invasive thyroid cancer took lenvatinib for a short time before their operation. The goal was to see if more patients could have clear or nearl…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Eye drop may prevent eyelash regrowth after trachoma surgery
Disease control CompletedThis study tested whether a steroid eye drop (fluorometholone) given for four weeks after trachoma surgery could stop eyelashes from growing back and rubbing against the eye. Over 2,400 people aged 15 and older took part. The goal was to see if this simple, low-cost addition to s…
Phase: PHASE3 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could an eye injection ease thyroid eye disease? small trial tests safety
Disease control CompletedThis Phase 2 trial tested whether injections of aflibercept, a drug that blocks abnormal blood vessel growth, are safe for people with active thyroid eye disease. Eleven adults received three injections over a month, with or without hyaluronidase to help spread the drug. The main…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Blood test shows promise for anal cancer screening
Diagnosis CompletedThis study tested a simple blood test to screen for anal dysplasia, a precancerous condition linked to HPV. Researchers enrolled 104 people with past or current anal HPV, plus some healthy controls. The goal was to see if the blood test could detect and classify anal dysplasia wi…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Jun 27, 2026 12:25 UTC
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Blood test spots hidden cancer after surgery in HPV head & neck patients
Diagnosis CompletedThis study tested a new blood test (liquid biopsy) to see if it could find any cancer left behind after surgery in 103 people with HPV-related head and neck cancer. The goal was to catch remaining disease early, which could help doctors decide if more treatment is needed. The tes…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC